Literature DB >> 3941898

Alterations of myc, myb, and rasHa proto-oncogenes in cancers are frequent and show clinical correlation.

J Yokota, Y Tsunetsugu-Yokota, H Battifora, C Le Fevre, M J Cline.   

Abstract

Alterations of c-myc, c-rasHa, or c-myb oncogenes were found in more than one-third of human solid tumors. Amplification of c-myc occurred in advanced, widespread tumors or in aggressive primary tumors. Apparent allelic deletions of c-rasHa and c-myb can be correlated with progression and metastasis of carcinomas and sarcomas.

Entities:  

Mesh:

Substances:

Year:  1986        PMID: 3941898     DOI: 10.1126/science.3941898

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  74 in total

1.  Distinct cellular factors regulate the c-myb promoter through its E2F element.

Authors:  M R Campanero; M Armstrong; E Flemington
Journal:  Mol Cell Biol       Date:  1999-12       Impact factor: 4.272

2.  Chromosomal and extrachromosomal instability of the cyclin D2 gene is induced by Myc overexpression.

Authors:  S Mai; J Hanley-Hyde; G J Rainey; T I Kuschak; J T Paul; T D Littlewood; H Mischak; L M Stevens; D W Henderson; J F Mushinski
Journal:  Neoplasia       Date:  1999-08       Impact factor: 5.715

3.  Discrimination of normal and transformed cells in vitro by cytologic and morphologic analysis.

Authors:  C D Albright; R Hay; R T Jones; J H Resau
Journal:  Cytotechnology       Date:  1989-08       Impact factor: 2.058

4.  Comparison of deoxyribonucleic acid ploidy and nuclear expressed p62 c-myc oncogene in the prognosis of colorectal cancer.

Authors:  S Rowley; K M Newbold; J Gearty; M R Keighley; I A Donovan; J P Neoptolemos
Journal:  World J Surg       Date:  1990 Jul-Aug       Impact factor: 3.352

5.  The spectrum of molecular alterations in the evolution of chronic myelocytic leukemia.

Authors:  H Ahuja; M Bar-Eli; Z Arlin; S Advani; S L Allen; J Goldman; D Snyder; A Foti; M Cline
Journal:  J Clin Invest       Date:  1991-06       Impact factor: 14.808

6.  Karyotype peculiarities of human colorectal adenocarcinomas.

Authors:  L N Konstantinova; E W Fleischman; V I Knisch; A G Perevozchikov; B P Kopnin
Journal:  Hum Genet       Date:  1991-03       Impact factor: 4.132

Review 7.  RAS inhibitors in hematologic cancers: biologic considerations and clinical applications.

Authors:  D M Beaupre; R Kurzrock
Journal:  Invest New Drugs       Date:  1999       Impact factor: 3.850

8.  Alterations of class I HLA genes in human colon cancers.

Authors:  M Bar-Eli; H Battifora; M J Cline
Journal:  Hum Genet       Date:  1988-01       Impact factor: 4.132

9.  Ras levels and metalloproteinase activity in normal versus neoplastic rat mammary tissues.

Authors:  M Ballin; A R Mackay; J L Hartzler; A Nason; M D Pelina; U P Thorgeirsson
Journal:  Clin Exp Metastasis       Date:  1991 Mar-Apr       Impact factor: 5.150

Review 10.  Genetics of colon cancer.

Authors:  D J Ahnen
Journal:  West J Med       Date:  1991-06
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.