Literature DB >> 3937549

Terfenadine and placebo compared in the treatment of chronic idiopathic urticaria: a randomised double-blind study.

J Ferguson, K J MacDonald, K J Kenicer.   

Abstract

Terfenadine, a potent and non-sedative antihistamine, was shown to be effective in chronic idiopathic urticaria in a double-blind crossover placebo controlled trial. An oral twice daily 60 mg dose of terfenadine was given and itch and wheal parameters were assessed daily. Despite the overall effectiveness of terfenadine, a variable response was noted which was similar to that shown in previous studies with other antihistamines.

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Year:  1985        PMID： 3937549      PMCID： PMC1400841          DOI： 10.1111/j.1365-2125.1985.tb05122.x

Source DB:  PubMed          Journal:  Br J Clin Pharmacol        ISSN： 0306-5251            Impact factor:   4.335


  10 in total

1.  Inhibitory activity of terfenadine on histamine-induced skin wheals in man.

Authors:  K J Hüther; G Renftle; N Barraud; J T Burke; J Koch-Weser
Journal:  Eur J Clin Pharmacol       Date:  1977-11-14       Impact factor: 2.953

2.  Chronopharmacological study of antihistamines in man with special references to terfenadine.

Authors:  A Reinberg; F Levi; P Guillet; J T Burke; A Nicolai
Journal:  Eur J Clin Pharmacol       Date:  1978-12-01       Impact factor: 2.953

3.  Urticaria and angio-oedema. A review of 554 patients.

Authors:  R H Champion; S O Roberts; R G Carpenter; J H Roger
Journal:  Br J Dermatol       Date:  1969-08       Impact factor: 9.302

4.  The pathogenic basis of urticaria and angioedema: recent advances.

Authors:  A P Kaplan
Journal:  Am J Med       Date:  1981-04       Impact factor: 4.965

5.  Treatment of chronic idiopathic urticaria with terfenadine.

Authors:  R Cerio; M H Lessof
Journal:  Clin Allergy       Date:  1984-03

6.  Assessment of tissue fluid histamine levels in patients with urticaria.

Authors:  A P Kaplan; Z Horáková; S I Katz
Journal:  J Allergy Clin Immunol       Date:  1978-06       Impact factor: 10.793

7.  Performance studies with the H1-histamine receptor antagonists, astemizole and terfenadine.

Authors:  A N Nicholson; B M Stone
Journal:  Br J Clin Pharmacol       Date:  1982-02       Impact factor: 4.335

8.  Sedation and antihistaminics.

Authors:  M Weiner
Journal:  Arzneimittelforschung       Date:  1982

9.  Terfenadine, the first non-sedating antihistamine.

Authors:  J K Woodward; N L Munro
Journal:  Arzneimittelforschung       Date:  1982

10.  Combined H1 and H2 antihistamine therapy in chronic urticaria.

Authors:  E W Monroe; S H Cohen; J Kalbfleisch; C I Schulz
Journal:  Arch Dermatol       Date:  1981-07
  10 in total
  5 in total

Review 1.  Placebo effects on itch: a meta-analysis of clinical trials of patients with dermatological conditions.

Authors:  Antoinette I M van Laarhoven; Ineke M van der Sman-Mauriks; A Rogier T Donders; Mathilde C Pronk; Peter C M van de Kerkhof; Andrea W M Evers
Journal:  J Invest Dermatol       Date:  2014-12-01       Impact factor: 8.551

Review 2.  Terfenadine. The first nonsedating antihistamine.

Authors:  H C Masheter
Journal:  Clin Rev Allergy       Date:  1993

3.  Long-term bradycardia caused by atrioventricular block can remodel the canine heart to detect the histamine H1 blocker terfenadine-induced torsades de pointes arrhythmias.

Authors:  Akira Takahara; Atsushi Sugiyama; Yuko Ishida; Yoshioki Satoh; Kai Wang; Yuji Nakamura; Keitaro Hashimoto
Journal:  Br J Pharmacol       Date:  2006-03       Impact factor: 8.739

Review 4.  Histamine2 (H2)-receptor antagonists in the treatment of urticaria.

Authors:  T C Theoharides
Journal:  Drugs       Date:  1989-03       Impact factor: 9.546

Review 5.  Terfenadine. An updated review of its pharmacological properties and therapeutic efficacy.

Authors:  D McTavish; K L Goa; M Ferrill
Journal:  Drugs       Date:  1990-04       Impact factor: 9.546
  5 in total

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