Literature DB >> 3930283

Urogastrone-epidermal growth factor is trophic to the intestinal epithelium of parenterally fed rats.

R A Goodlad, T J Wilson, W Lenton, H Gregory, K G McCullough, N A Wright.   

Abstract

The weight of the stomach, small intestine and colon and the mucosal crypt cell production rate of these tissues were significantly decreased after 10 days on an isocaloric TPN diet when compared to orally fed controls. Continuous infusion of recombinant beta urogastrone, at a dose below that needed to inhibit gastric acid secretion, largely prevented this decrease in crypt cell production rate and gastrointestinal tissue weights.

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Year:  1985        PMID: 3930283     DOI: 10.1007/bf01951708

Source DB:  PubMed          Journal:  Experientia        ISSN: 0014-4754


  21 in total

1.  Epidermal growth factor stimulates ornithine decarboxylase activity in the digestive tract of mouse.

Authors:  E J Feldman; D Aures; M I Grossman
Journal:  Proc Soc Exp Biol Med       Date:  1978-12

2.  Immunohistochemical localisation of urogastrone to human duodenal and submandibular glands.

Authors:  P U Heitz; M Kasper; S van Noorden; J M Polak; H Gregory; A G Pearse
Journal:  Gut       Date:  1978-05       Impact factor: 23.059

3.  Influence of epidermal growth factor on the development of suckling mouse intestinal mucosa.

Authors:  C Malo; D Ménard
Journal:  Gastroenterology       Date:  1982-07       Impact factor: 22.682

4.  Demonstration of specific receptors for EGF--urogastrone in isolated rat intestinal epithelial cells.

Authors:  M E Forgue-Lafitte; M Laburthe; M C Chamblier; A J Moody; G Rosselin
Journal:  FEBS Lett       Date:  1980-06-02       Impact factor: 4.124

5.  Circadian phase-dependent stimulatory effects of epidermal growth factor on deoxyribonucleic acid synthesis in the tongue, esophagus, and stomach of the adult male mouse.

Authors:  L A Scheving; Y C Yeh; T H Tsai; L E Scheving
Journal:  Endocrinology       Date:  1979-12       Impact factor: 4.736

6.  The effect of epidermal growth factor (EGF) on cell proliferation of the gastrointestinal mucosa in rodents.

Authors:  A I Al-Nafussi; N A Wright
Journal:  Virchows Arch B Cell Pathol Incl Mol Pathol       Date:  1982

7.  Epidermal growth factor inhibits cysteamine-induced duodenal ulcers.

Authors:  P Kirkegaard; P S Olsen; S S Poulsen; E Nexø
Journal:  Gastroenterology       Date:  1983-12       Impact factor: 22.682

8.  Stimulation of rat oxyntic gland mucosal growth by epidermal growth factor.

Authors:  L R Johnson; P D Guthrie
Journal:  Am J Physiol       Date:  1980-01

9.  Hypersecretion of submandibular saliva in male mice: trophic response in small intestine.

Authors:  A K Li; M E Schattenkerk; R G Huffman; J S Ross; R A Malt
Journal:  Gastroenterology       Date:  1983-05       Impact factor: 22.682

10.  Effect of mouse epidermal growth factor/urogastrone on the functional maturation of rat intestine.

Authors:  Y Oka; F K Ghishan; H L Greene; D N Orth
Journal:  Endocrinology       Date:  1983-03       Impact factor: 4.736

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  11 in total

1.  Effects of urogastrone-epidermal growth factor on intestinal brush border enzymes and mitotic activity.

Authors:  R A Goodlad; K B Raja; T J Peters; N A Wright
Journal:  Gut       Date:  1991-09       Impact factor: 23.059

2.  Simultaneous measurement of intestinal crypt cell production rate and water absorption.

Authors:  R A Goodlad; J A Plumb; N A Wright
Journal:  Gut       Date:  1987       Impact factor: 23.059

3.  Intravenous but not intragastric urogastrone-EGF is trophic to the intestine of parenterally fed rats.

Authors:  R A Goodlad; T J Wilson; W Lenton; H Gregory; K G McCullagh; N A Wright
Journal:  Gut       Date:  1987-05       Impact factor: 23.059

4.  The trophic effect of epidermal growth factor on morphological changes and polyamine metabolism in the small intestine of rats.

Authors:  T Tsujikawa; T Bamba; S Hosoda
Journal:  Gastroenterol Jpn       Date:  1990-06

Review 5.  Peptides and epithelial growth regulation.

Authors:  R A Goodlad; N A Wright
Journal:  Experientia       Date:  1987-07-15

6.  Trophic action of epidermal growth factor on human duodenal mucosa cultured in vitro.

Authors:  D N Challacombe; E E Wheeler
Journal:  Gut       Date:  1991-09       Impact factor: 23.059

7.  Proliferative effects of urogastrone-EGF on the intestinal epithelium.

Authors:  R A Goodlad; T J Wilson; W Lenton; H Gregory; K G McCullagh; N A Wright
Journal:  Gut       Date:  1987       Impact factor: 23.059

8.  Plasma enteroglucagon, peptide YY and gastrin in rats deprived of luminal nutrition, and after urogastrone-EGF administration. A proliferative role for PYY in the intestinal epithelium?

Authors:  R A Goodlad; M A Ghatei; J Domin; S R Bloom; H Gregory; N A Wright
Journal:  Experientia       Date:  1989-02-15

9.  Effect of epidermal growth factor by different routes of administration on the small intestinal mucosa of rats fed elemental diet.

Authors:  T Bamba; T Tsujikawa; S Hosoda
Journal:  Gastroenterol Jpn       Date:  1993-08

10.  Tyrosine phosphorylation in the human duodenum.

Authors:  D Kelleher; A Murphy; O Sheils; A Long; J McDevitt
Journal:  Gut       Date:  1995-01       Impact factor: 23.059

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