Literature DB >> 3928525

Monotherapy and polytherapy for intractable epilepsies.

C Cornaggia, M P Canevini, D Giuccioli, P Pinelli, C Pruneri, R Canger.   

Abstract

A retrospective survey on 66 adults with epilepsy who received multiple drug therapy after the failure of single drugs showed: a reduction of seizure frequency of 75% or more in 16.5%, no change in 67% and an increase in seizure frequency of 100% or more in 16.5%. Multiple drug therapy is of limited value in severe epilepsies.

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Year:  1985        PMID: 3928525     DOI: 10.1007/bf02229193

Source DB:  PubMed          Journal:  Ital J Neurol Sci        ISSN: 0392-0461


  7 in total

1.  Reduction in polypharmacy for epilepsy.

Authors:  S D Shorvon; E H Reynolds
Journal:  Br Med J       Date:  1979-10-27

2.  Rapid identification and quantitative determination of barbiturates and glutethimide in blood by gas-liquid chromatography.

Authors:  J MacGee
Journal:  Clin Chem       Date:  1971-07       Impact factor: 8.327

3.  Amino acid content of epileptogenic human brain: focal versus surrounding regions.

Authors:  N M Van Gelder; A L Sherwin; T Rasmussen
Journal:  Brain Res       Date:  1972-05-26       Impact factor: 3.252

4.  One drug (phenytoin) in the treatment of epilepsy.

Authors:  E H Reynolds; D Chadwick; A W Galbraith
Journal:  Lancet       Date:  1976-05-01       Impact factor: 79.321

5.  Unnecessary polypharmacy for epilepsy.

Authors:  S D Shorvon; E H Reynolds
Journal:  Br Med J       Date:  1977-06-25

6.  Two antiepileptic drugs for intractable epilepsy with complex-partial seizures.

Authors:  D Schmidt
Journal:  J Neurol Neurosurg Psychiatry       Date:  1982-12       Impact factor: 10.154

7.  Monotherapy or polytherapy for epilepsy?

Authors:  E H Reynolds; S D Shorvon
Journal:  Epilepsia       Date:  1981-02       Impact factor: 5.864

  7 in total
  1 in total

1.  Carbamazepine, phenytoin and phenobarbital in drug-resistant partial epilepsies.

Authors:  C M Cornaggia; M P Canevini; D Giuccioli; C Pruneri; R Canger
Journal:  Ital J Neurol Sci       Date:  1986-02
  1 in total

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