Literature DB >> 3927355

Changes in human platelet 5 HT level after 1 week of chlorimipramine treatment.

M F Poirier, K H Le Quan-Bui, H Lôo, P Meyer.   

Abstract

In platelets of six volunteers taking chlorimipramine (50 mg/day) for 1 week, 5-HT levels were markedly decreased at the time of treatment withdrawal, and remained significantly reduced after a 1-week washout. Individual levels in five subjects remained affected during a 3-week washout. The previously reported observations of reduced serotonin concentration in platelets from depressed patients may reflect a residual effect of previous antidepressant treatment.

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Year:  1985        PMID： 3927355     DOI： 10.1007/bf00431708

Source DB:  PubMed          Journal:  Psychopharmacology (Berl)        ISSN： 0033-3158            Impact factor:   4.530


  12 in total

1.  5-Hydroxytryptamine (5-HT) in the whole-blood of patients with depressive illness.

Authors:  A Coppen; P Turner; A R Rowsell; C Padgham
Journal:  Postgrad Med J       Date:  1976-03       Impact factor: 2.401

2.  Decreased uptake of 5-hydroxytryptamine in blood platelets from depressed patients.

Authors:  J Tuomisto; E Tukiainen
Journal:  Nature       Date:  1976-08-12       Impact factor: 49.962

3.  Inhibition of 5-hydroxytryptamine uptake in human platelets by antidepressant agents in vivo.

Authors:  S B Ross; B Aperia; J Beck-Friis; S Jansa; L Wetterberg; A Aberg
Journal:  Psychopharmacology (Berl)       Date:  1980-01       Impact factor: 4.530

4.  Reduction of blood platelet serotonin levels in manic and depressed patients.

Authors:  S Takahashi
Journal:  Folia Psychiatr Neurol Jpn       Date:  1976

5.  Long-term effect of lithium on the uptake of 5-hydroxytryptamine by human platelets.

Authors:  G V Born; G Grignani; K Martin
Journal:  Br J Clin Pharmacol       Date:  1980-04       Impact factor: 4.335

6.  [3H]Imipramine binding and [3H]5HT uptake in human blood platelets: changes after one week chlorimipramine treatment.

Authors:  M F Poirier; H Loo; C Benkelfat; D Sechter; E Zarifian; A M Galzin; H Schoemaker; A Segonzac; S Z Langer
Journal:  Eur J Pharmacol       Date:  1984-11-27       Impact factor: 4.432

7.  Serotonin uptake in blood platelets of psychiatric patients.

Authors:  H Y Meltzer; R C Arora; R Baber; B J Tricou
Journal:  Arch Gen Psychiatry       Date:  1981-12

8.  Reduced platelet serotonin in depression.

Authors:  K H Le Quan-Bui; O Plaisant; M Leboyer; C Gay; L Kamal; M A Devynck; P Meyer
Journal:  Psychiatry Res       Date:  1984-10       Impact factor: 3.222

9.  Increased platelet serotonin in bipolar depression and hypomania.

Authors:  A Wirz-Justice; W Pühringer
Journal:  J Neural Transm       Date:  1978       Impact factor: 3.575

10.  Hyperserotonemia and platelet serotonin uptake and release in schizophrenia and affective disorders.

Authors:  S M Stahl; D J Woo; I N Mefford; P A Berger; R D Ciaranello
Journal:  Am J Psychiatry       Date:  1983-01       Impact factor: 18.112
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  3 in total

1.  Short-term lithium administration to healthy volunteers produces long-lasting pronounced changes in platelet serotonin uptake but not imipramine binding.

Authors:  M F Poirier; A M Galzin; C Pimoule; H Schoemaker; K H Le Quan Bui; P Meyer; C Gay; H Loo; S Z Langer
Journal:  Psychopharmacology (Berl)       Date:  1988       Impact factor: 4.530

2.  Increased plasma free serotonin but unchanged platelet serotonin in bipolar patients treated chronically with lithium.

Authors:  F Artigas; M J Sarrias; E Martínez; E Gelpí; E Alvarez; C Udina
Journal:  Psychopharmacology (Berl)       Date:  1989       Impact factor: 4.530

3.  Milnacipran treatment and potential biomarkers in depressed patients following an initial SSRI treatment failure: a prospective, open-label, 24-week study.

Authors:  Tasuku Hashimoto; Daiji Sakurai; Yasunori Oda; Tadashi Hasegawa; Nobuhisa Kanahara; Tsuyoshi Sasaki; Hideki Komatsu; Junpei Takahashi; Takahiro Oiwa; Yoshimoto Sekine; Hiroyuki Watanabe; Masaomi Iyo
Journal:  Neuropsychiatr Dis Treat       Date:  2015-12-10       Impact factor: 2.570
  3 in total

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