Literature DB >> 3926653

Detection of Mycoplasma pneumoniae adhesin (P1) in the nonhemadsorbing population of virulent Mycoplasma pneumoniae.

I Kahane, S Tucker, J B Baseman.   

Abstract

Mycoplasma pneumoniae organisms possessing a hemadsorbing-negative (HA-) phenotype comprise more than 50% of the population of virulent M. pneumoniae cultures. Monoclonal antibody to P1, the major adhesin of M. pneumoniae reacts with this HA- mycoplasma fraction based upon radioimmunoprecipitation and immunoblotting. Demonstration of P1 in the entire mycoplasma population suggests that topological organization of this adhesin in the membrane or the physiological state of the mycoplasmas may determine hemadsorbing capabilities.

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Year:  1985        PMID： 3926653      PMCID： PMC262042          DOI： 10.1128/iai.49.2.457-458.1985

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  15 in total

1.  Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

Authors:  H Towbin; T Staehelin; J Gordon
Journal:  Proc Natl Acad Sci U S A       Date:  1979-09       Impact factor: 11.205

2.  A film detection method for tritium-labelled proteins and nucleic acids in polyacrylamide gels.

Authors:  W M Bonner; R A Laskey
Journal:  Eur J Biochem       Date:  1974-07-01

3.  Tissue cultures and mycoplasmas.

Authors:  L Hayflick
Journal:  Tex Rep Biol Med       Date:  1965-06

4.  Mycoplasma pneumoniae infection: role of a surface protein in the attachment organelle.

Authors:  P C Hu; R M Cole; Y S Huang; J A Graham; D E Gardner; A M Collier; W A Clyde
Journal:  Science       Date:  1982-04-16       Impact factor: 47.728

5.  Mycoplasma pneumoniae proteins that selectively bind to host cells.

Authors:  D C Krause; J B Baseman
Journal:  Infect Immun       Date:  1982-07       Impact factor: 3.441

6.  Isolation of binding sites to glycophorin from Mycoplasma pneumoniae membranes.

Authors:  M Banai; S Razin; W Bredt; I Kahane
Journal:  Infect Immun       Date:  1980-12       Impact factor: 3.441

7.  Mycoplasma pneumoniae adhesin localized to tip structure by monoclonal antibody.

Authors:  J Feldner; U Göbel; W Bredt
Journal:  Nature       Date:  1982-08-19       Impact factor: 49.962

8.  Purification of a Mycoplasma pneumoniae adhesin by monoclonal antibody affinity chromatography.

Authors:  D K Leith; J B Baseman
Journal:  J Bacteriol       Date:  1984-02       Impact factor: 3.490

9.  Molecular basis for cytadsorption of Mycoplasma pneumoniae.

Authors:  J B Baseman; R M Cole; D C Krause; D K Leith
Journal:  J Bacteriol       Date:  1982-09       Impact factor: 3.490

10.  Surface parasitism by Mycoplasma pneumoniae of respiratory epithelium.

Authors:  P C Hu; A M Collier; J B Baseman
Journal:  J Exp Med       Date:  1977-05-01       Impact factor: 14.307
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  6 in total

1.  Restriction fragment length polymorphism in the cytadhesin P1 gene of human clinical isolates of Mycoplasma pneumoniae.

Authors:  S F Dallo; J R Horton; C J Su; J B Baseman
Journal:  Infect Immun       Date:  1990-06       Impact factor: 3.441

2.  Biological effects of anti-lipid and anti-protein monoclonal antibodies on Mycoplasma pneumoniae.

Authors:  J Morrison-Plummer; D K Leith; J B Baseman
Journal:  Infect Immun       Date:  1986-08       Impact factor: 3.441

3.  Regions of Mycoplasma pneumoniae cytadhesin P1 structural gene exist as multiple copies.

Authors:  C J Su; A Chavoya; J B Baseman
Journal:  Infect Immun       Date:  1988-12       Impact factor: 3.441

4.  The principal protein antigens of isolates of Mycoplasma pneumoniae as measured by levels of immunoglobulin G in human serum are stable in strains collected over a 10-year period.

Authors:  A C Vu; H M Foy; F D Cartwright; G E Kenny
Journal:  Infect Immun       Date:  1987-08       Impact factor: 3.441

5.  Cloning and sequence analysis of cytadhesin P1 gene from Mycoplasma pneumoniae.

Authors:  C J Su; V V Tryon; J B Baseman
Journal:  Infect Immun       Date:  1987-12       Impact factor: 3.441

6.  Identification of P1 gene domain containing epitope(s) mediating Mycoplasma pneumoniae cytoadherence.

Authors:  S F Dallo; C J Su; J R Horton; J B Baseman
Journal:  J Exp Med       Date:  1988-02-01       Impact factor: 14.307
  6 in total

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