| Literature DB >> 3926627 |
Abstract
Kinship mapping and population supratypes provide information on order and relative genetic position of loci within a system too small to map by recombination. These methods are compared for the RH, beta-globin, HLA, and GM systems, where recombination between loci is estimated as 0.0002-0.0069. Supratype analysis does not appreciably improve kinship mapping. Mean recombination within systems appears to be 10(-4) morgans/kb, an order of magnitude greater than the average for the whole genome. Possible implications of this discrepancy are discussed.Mesh:
Substances:
Year: 1985 PMID: 3926627 DOI: 10.1007/bf00273447
Source DB: PubMed Journal: Hum Genet ISSN: 0340-6717 Impact factor: 4.132