| Literature DB >> 3925293 |
Abstract
Plasmid pC194-1, a mutant of pC194, and chimeric derivatives of pC194-1 are segregationally unstable in B. subtilis. Such instability could be enhanced by exposure of pC194-1-carrying cells to methyl methanesulfonate. pC194-1 is distinct from pC194 in the addition of two A:T base pairs within the previously defined D region of pC194. Complementation experiments between pC194-1 and other plasmids suggest that the mutation of pC194-1 interferes with the production of a diffusible gene product required for plasmid maintenance.Entities:
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Year: 1985 PMID: 3925293 DOI: 10.1007/bf00332934
Source DB: PubMed Journal: Mol Gen Genet ISSN: 0026-8925