| Literature DB >> 3925068 |
R L Kirkman, L V Barrett, G N Gaulton, V E Kelley, A Ythier, T B Strom.
Abstract
Administration of the monoclonal antibody M7/20, which binds to the murine interleukin-2 (IL) receptor, significantly prolongs cardiac allograft survival in two H-2-incompatible strain combinations of inbred mice. The results support the important role of the IL-2 receptor in the mechanism of graft rejection, and suggest its suitability as a target for immunosuppressive therapy.Entities:
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Year: 1985 PMID: 3925068 PMCID: PMC2187689 DOI: 10.1084/jem.162.1.358
Source DB: PubMed Journal: J Exp Med ISSN: 0022-1007 Impact factor: 14.307