Literature DB >> 3923957

Hypophyseal-gonadal system during male aging.

E V Moroz, N S Verkhratsky.   

Abstract

The concentration of sex and gonadotropic hormones in blood plasma of 280 reasonably healthy men aged 20-105 was determined using radioimmunoassay kits. Compared to men aged 20-39, the statistically significant decrease in testosterone level was registered in men aged 55-59, the increase in oestradiol in men aged 60-64, progesterone in men aged 55-59, and in LH and FSH in the group aged 65-69. The reactivity of central and peripheral links of the hypothalamic-gonadal system to direct and feed-back control influences alters with age.

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Year:  1985        PMID: 3923957     DOI: 10.1016/0167-4943(85)90013-5

Source DB:  PubMed          Journal:  Arch Gerontol Geriatr        ISSN: 0167-4943            Impact factor:   3.250


  5 in total

Review 1.  Sex as a Biological Variable: Who, What, When, Why, and How.

Authors:  Tracy L Bale; C Neill Epperson
Journal:  Neuropsychopharmacology       Date:  2016-09-23       Impact factor: 7.853

Review 2.  Age-related changes in male gonadal function. Implications for therapy.

Authors:  D Maas; A Jochen; B Lalande
Journal:  Drugs Aging       Date:  1997-07       Impact factor: 3.923

3.  The FSHB -211G>T variant attenuates serum FSH levels in the supraphysiological gonadotropin setting of Klinefelter syndrome.

Authors:  Alexander S Busch; Frank Tüttelmann; Michael Zitzmann; Sabine Kliesch; Jörg Gromoll
Journal:  Eur J Hum Genet       Date:  2014-07-23       Impact factor: 4.246

4.  Attenuated release of biologically active luteinizing hormone in healthy aging men.

Authors:  R J Urban; J D Veldhuis; R M Blizzard; M L Dufau
Journal:  J Clin Invest       Date:  1988-04       Impact factor: 14.808

5.  Serum sex steroids, gonadotrophins and sex hormone-binding globulin in prostatic hyperplasia.

Authors:  Mohammad Abdul Jalil Ansari; Dilruba Begum; Fakhrul Islam
Journal:  Ann Saudi Med       Date:  2008 May-Jun       Impact factor: 1.526

  5 in total

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