Literature DB >> 3922604

Pig interleukin 1 (catabolin) is a potent stimulator of bone resorption in vitro.

J K Heath, J Saklatvala, M C Meikle, S J Atkinson, J J Reynolds.   

Abstract

A homogeneous form of pig interleukin 1 (catabolin) stimulates the resorption of mouse bones in culture. Concentrations as low as 25 pM are effective, demonstrating that it is more potent than 1,25-dihydroxy-vitamin D3 in our assay system. Catabolin was originally defined by its ability to stimulate glycosaminoglycan release from cartilage in culture and purified from pig mononuclear leucocyte supernatants. It also augments lectin-induced thymocyte proliferation, indicating that it is a form of pig interleukin 1. Bone resorbing factors are synthesized by other cell types, including fibroblasts and osteoblasts; we suggest that such cytokines are important in mediating the action of systemic hormones on bone.

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Year:  1985        PMID： 3922604     DOI： 10.1007/bf02557686

Source DB:  PubMed          Journal:  Calcif Tissue Int        ISSN： 0171-967X            Impact factor:   4.333


  11 in total

1.  The role of vitamin D metabolites in bone resorption.

Authors:  J J Reynolds; M F Holick; H F De Luca
Journal:  Calcif Tissue Res       Date:  1973

2.  A factor synthesized by rabbit periosteal fibroblasts stimulates bone resorption and collagenase production by connective tissue cells in vitro.

Authors:  J K Heath; M C Meikle; S J Atkinson; J J Reynolds
Journal:  Biochim Biophys Acta       Date:  1984-08-21

3.  Role of osteoblasts in hormonal control of bone resorption--a hypothesis.

Authors:  G A Rodan; T J Martin
Journal:  Calcif Tissue Int       Date:  1981       Impact factor: 4.333

4.  Stimulation of bone resorption in vitro by a non-prostanoid factor released by human monocytes in culture.

Authors:  M Gowen; M C Meikle; J J Reynolds
Journal:  Biochim Biophys Acta       Date:  1983-06-02

5.  Purification of a lymphokine: osteoclast activating factor from human tonsil lymphocytes.

Authors:  R A Luben
Journal:  Biochem Biophys Res Commun       Date:  1978-09-14       Impact factor: 3.575

6.  Stimulation by human interleukin 1 of cartilage breakdown and production of collagenase and proteoglycanase by human chondrocytes but not by human osteoblasts in vitro.

Authors:  M Gowen; D D Wood; E J Ihrie; J E Meats; R G Russell
Journal:  Biochim Biophys Acta       Date:  1984-02-14

7.  Purification to homogeneity of pig leucocyte catabolin, a protein that causes cartilage resorption in vitro.

Authors:  J Saklatvala; V A Curry; S J Sarsfield
Journal:  Biochem J       Date:  1983-11-01       Impact factor: 3.857

8.  Pig catabolin is a form of interleukin 1. Cartilage and bone resorb, fibroblasts make prostaglandin and collagenase, and thymocyte proliferation is augmented in response to one protein.

Authors:  J Saklatvala; L M Pilsworth; S J Sarsfield; J Gavrilovic; J K Heath
Journal:  Biochem J       Date:  1984-12-01       Impact factor: 3.857

9.  An interleukin 1 like factor stimulates bone resorption in vitro.

Authors:  M Gowen; D D Wood; E J Ihrie; M K McGuire; R G Russell
Journal:  Nature       Date:  1983 Nov 24-30       Impact factor: 49.962

10.  Lymphokine-mediated bone resorption requires endogenous prostaglandin synthesis.

Authors:  R S Bockman; M A Repo
Journal:  J Exp Med       Date:  1981-08-01       Impact factor: 14.307
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  27 in total

1.  Biologic markers for odontogenic periradicular periodontitis.

Authors:  Bruna Burgener; Angelique R Ford; Hongsa Situ; Mohamed I Fayad; Jian Jun Hao; Christopher S Wenckus; Bradford R Johnson; Ellen A BeGole; Anne George
Journal:  J Endod       Date:  2010-06-25       Impact factor: 4.171

2.  Effects of interleukin-1, tumor necrosis factor -beta, and forskolin on tissue plasminogen activator activity in human osteoblastic osteosarcoma cells.

Authors:  A C Kohl; D N Tatakis; C Hansen; R Dziak
Journal:  Calcif Tissue Int       Date:  1992-02       Impact factor: 4.333

Review 3.  Incidence and pathophysiology of hypercalcemia.

Authors:  G R Mundy
Journal:  Calcif Tissue Int       Date:  1990       Impact factor: 4.333

Review 4.  Control mechanisms in bone resorption: 240 years after John Hunter.

Authors:  M C Meikle
Journal:  Ann R Coll Surg Engl       Date:  1997-01       Impact factor: 1.891

5.  Osteoclast-like cells form in long-term human bone marrow but not in peripheral blood cultures.

Authors:  N Takahashi; T Kukita; B R MacDonald; A Bird; G R Mundy; L M McManus; M Miller; A Boyde; S J Jones; G D Roodman
Journal:  J Clin Invest       Date:  1989-02       Impact factor: 14.808

6.  Effect of meloxicam on gingival crevicular fluid IL-1beta and IL1 receptor antagonist levels in subjects with chronic periodontitis, and its effects on clinical parameters.

Authors:  Hulya Toker; Ismail Marakoglu; Omer Poyraz
Journal:  Clin Oral Investig       Date:  2006-08-01       Impact factor: 3.573

7.  Bone loss from high repetitive high force loading is prevented by ibuprofen treatment.

Authors:  N X Jain; A E Barr-Gillespie; B D Clark; D M Kietrys; C K Wade; J Litvin; S N Popoff; M F Barbe
Journal:  J Musculoskelet Neuronal Interact       Date:  2014-03       Impact factor: 2.041

8.  Stimulation of bone resorption by inflamed nasal mucosa, dermonecrotic toxin-containing conditioned medium from Pasteurella multocida, and purified dermonecrotic toxin from P. multocida.

Authors:  T G Kimman; C W Löwik; L J van de Wee-Pals; C W Thesingh; P Defize; E M Kamp; O L Bijvoet
Journal:  Infect Immun       Date:  1987-09       Impact factor: 3.441

9.  Recombinant human interleukin-1 alpha and recombinant human interleukin-1 beta stimulate cartilage matrix degradation and inhibit glycosaminoglycan synthesis.

Authors:  R J Smith; N A Rohloff; L M Sam; J M Justen; M R Deibel; J C Cornette
Journal:  Inflammation       Date:  1989-08       Impact factor: 4.092

10.  Tumor necrosis factor mediates endotoxic effects in mice.

Authors:  F Bauss; W Dröge; D N Männel
Journal:  Infect Immun       Date:  1987-07       Impact factor: 3.441
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