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Literature DB >> 3920959

Activities of new quinoline derivatives against genital pathogens.

J Aznar, M C Caballero, M C Lozano, C de Miguel, J C Palomares, E J Perea.

Abstract

The in vitro activities of four quinoline carboxylic acids against 48 strains of Neisseria gonorrhoeae, 10 of Chlamydia trachomatis, and 32 of Ureaplasma urealyticum were compared. Ciprofloxacin was the most active against N. gonorrhoeae and C. trachomatis but had poor bactericidal activity against U. urealyticum, whereas ofloxacin showed the most bactericidal activity against U. urealyticum but was less active than ciprofloxacin against the two former pathogens. Norfloxacin and enoxacin were less active against all the studied pathogens.

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Year: 1985 PMID： 3920959 PMCID： PMC176208 DOI： 10.1128/AAC.27.1.76

Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN： 0066-4804 Impact factor: 5.191

21 in total

1. A method for testing the antibiotic susceptibility of Chlamydia trachomatis in a cell culture system.

Authors: G L Ridgway; J M Owen; J D Oriel
Journal: J Antimicrob Chemother Date: 1976-03 Impact factor: 5.790

2. Etiology of nongonococcal urethritis. Evidence for Chlamydia trachomatis and Ureaplasma urealyticum.

Authors: W R Bowie; S P Wang; E R Alexander; J Floyd; P S Forsyth; H M Pollock; J S Lin; T M Buchanan; K K Holmes
Journal: J Clin Invest Date: 1977-05 Impact factor: 14.808

3. Comparative in vitro activity of Mk-0366 and other selected oral antimicrobial agents against Neisseria gonorrhoeae.

Authors: M Y Khan; Y Siddiqui; R P Gruninger
Journal: Antimicrob Agents Chemother Date: 1981-08 Impact factor: 5.191

4. Antimycoplasmal activity of ofloxacin (DL-8280).

Authors: Y Osada; H Ogawa
Journal: Antimicrob Agents Chemother Date: 1983-03 Impact factor: 5.191

5. Comparative evaluation of media for isolation of ureaplasma urealyticum and genital mycoplasma species.

Authors: D S Leland; M A Lapworth; R B Jones; M L French
Journal: J Clin Microbiol Date: 1982-10 Impact factor: 5.948

6. In vitro antibacterial activity of AM-715, a new nalidixic acid analog.

Authors: A Ito; K Hirai; M Inoue; H Koga; S Suzue; T Irikura; S Mitsuhashi
Journal: Antimicrob Agents Chemother Date: 1980-02 Impact factor: 5.191

7. In vitro and in vivo activity of DL-8280, a new oxazine derivative.

Authors: K Sato; Y Matsuura; M Inoue; T Une; Y Osada; H Ogawa; S Mitsuhashi
Journal: Antimicrob Agents Chemother Date: 1982-10 Impact factor: 5.191

8. In vitro susceptibility of Ureaplasma urealyticum to rosaramicin.

Authors: T F Smith
Journal: Antimicrob Agents Chemother Date: 1979-07 Impact factor: 5.191

9. The antimicrobial susceptibility of Chlamydia trachomatis in cell culture.

Authors: G L Ridgway; J M Owen; J D Oriel
Journal: Br J Vener Dis Date: 1978-04

10. Activity in vitro of ten antimicrobial agents against Neisseria gonorrhoeae. A study of the correlation between the sensitivities.

Authors: A Meheus; P Piot; S Pattyn; E van Dyck; D van den Berghe
Journal: Br J Vener Dis Date: 1976-10

27 in total

1. Comparison of ofloxacin and ceftriaxone in the treatment of uncomplicated gonorrhea caused by penicillinase-producing and non-penicillinase-producing strains.

Authors: J M Covino; M Cummings; B Smith; S Benes; K Draft; W M McCormack
Journal: Antimicrob Agents Chemother Date: 1990-01 Impact factor: 5.191

10. In vitro susceptibilities of Mycoplasma pneumoniae, Mycoplasma hominis, and Ureaplasma urealyticum to sparfloxacin and PD 127391.

Authors: K B Waites; L B Duffy; T Schmid; D Crabb; M S Pate; G H Cassell
Journal: Antimicrob Agents Chemother Date: 1991-06 Impact factor: 5.191

Activities of new quinoline derivatives against genital pathogens.

1. A method for testing the antibiotic susceptibility of Chlamydia trachomatis in a cell culture system.

2. Etiology of nongonococcal urethritis. Evidence for Chlamydia trachomatis and Ureaplasma urealyticum.

3. Comparative in vitro activity of Mk-0366 and other selected oral antimicrobial agents against Neisseria gonorrhoeae.

4. Antimycoplasmal activity of ofloxacin (DL-8280).

5. Comparative evaluation of media for isolation of ureaplasma urealyticum and genital mycoplasma species.

6. In vitro antibacterial activity of AM-715, a new nalidixic acid analog.

7. In vitro and in vivo activity of DL-8280, a new oxazine derivative.

8. In vitro susceptibility of Ureaplasma urealyticum to rosaramicin.

9. The antimicrobial susceptibility of Chlamydia trachomatis in cell culture.

10. Activity in vitro of ten antimicrobial agents against Neisseria gonorrhoeae. A study of the correlation between the sensitivities.

1. Comparison of ofloxacin and ceftriaxone in the treatment of uncomplicated gonorrhea caused by penicillinase-producing and non-penicillinase-producing strains.

2. In vitro activity of 14 antimicrobial agents against Neisseria gonorrhoeae from Spain.

3. The fluoroquinolones: structures, mechanisms of action and resistance, and spectra of activity in vitro.

Review 4. Quinolone antibacterial agents for the treatment of genitourinary tract infections.

5. In vitro activities of temafloxacin (A-62254) and four other antibiotics against Chlamydia trachomatis.

6. Susceptibilities of genital mycoplasmas to the newer quinolones as determined by the agar dilution method.

7. Effect of ofloxacin on Treponema pallidum in incubating experimental syphilis.

8. The place of quinolones in antibacterial therapy in hospitals.

9. Failure of norfloxacin to eradicate Chlamydia trachomatis in nongonococcal urethritis.

10. In vitro susceptibilities of Mycoplasma pneumoniae, Mycoplasma hominis, and Ureaplasma urealyticum to sparfloxacin and PD 127391.