Literature DB >> 3919444

Human T-cell receptor alpha-chain genes: location on chromosome 14.

C Jones, H G Morse, F T Kao, A Carbone, E Palmer.   

Abstract

The genes encoding the alpha chain of the human T-cell receptor have been mapped to chromosome 14, the chromosome on which the human immunoglobulin heavy chain locus resides. Thus, genes encoding two different classes of antigen receptor are present on the same chromosome. Furthermore, breaks involving chromosome 14 are frequently seen in tumors of T-cell origin. The potential relation of these chromosome abnormalities to alpha-chain genes is discussed.

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Year:  1985        PMID： 3919444     DOI： 10.1126/science.3919444

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  17 in total

1.  Localization of the amphotropic murine leukemia virus receptor gene to the pericentromeric region of human chromosome 8.

Authors:  J V Garcia; C Jones; A D Miller
Journal:  J Virol       Date:  1991-11       Impact factor: 5.103

2.  Mapping of the gene encoding the multifunctional protein carrying out the first three steps of pyrimidine biosynthesis to human chromosome 2.

Authors:  K C Chen; D B Vannais; C Jones; D Patterson; J N Davidson
Journal:  Hum Genet       Date:  1989-04       Impact factor: 4.132

Review 3.  T-cell clones and T-cell receptors.

Authors:  F W Fitch
Journal:  Microbiol Rev       Date:  1986-03

4.  Inverted duplication of JH associated with chromosome 14 translocation and T-cell leukemia in ataxia-telangiectasia.

Authors:  J P Johnson; R A Gatti; T S Sears; R L White
Journal:  Am J Hum Genet       Date:  1986-12       Impact factor: 11.025

5.  The gene for the human immune interferon receptor is located on chromosome 6.

Authors:  A Rashidbaigi; J A Langer; V Jung; C Jones; H G Morse; J A Tischfield; J J Trill; H F Kung; S Pestka
Journal:  Proc Natl Acad Sci U S A       Date:  1986-01       Impact factor: 11.205

6.  Single cell translocations in couples with multiple spontaneous abortions.

Authors:  M D Higgins; C G Palmer
Journal:  Hum Genet       Date:  1987-01       Impact factor: 4.132

7.  The gene encoding the hydrophobic surfactant protein SP-C is located on 8p and identifies an EcoRI RFLP.

Authors:  J H Fisher; P A Emrie; H A Drabkin; T Kushnik; M Gerber; T Hofmann; C Jones
Journal:  Am J Hum Genet       Date:  1988-10       Impact factor: 11.025

8.  Restriction fragment length polymorphism of the human T cell receptor alpha gene. I. Two polymorphic restriction sites localized to different regions of the gene.

Authors:  E J Ball; L Dombrausky; M Hoover; J D Capra; P Stastny
Journal:  Immunogenetics       Date:  1987       Impact factor: 2.846

9.  The coding sequence for the 32,000-dalton pulmonary surfactant-associated protein A is located on chromosome 10 and identifies two separate restriction-fragment-length polymorphisms.

Authors:  J H Fisher; F T Kao; C Jones; R T White; B J Benson; R J Mason
Journal:  Am J Hum Genet       Date:  1987-06       Impact factor: 11.025

10.  Restriction length polymorphism in the variable region of the Tcr locus linked to histocompatibility antigen H-8 on murine chromosome 14.

Authors:  J W Berman; A J Rocha; R Basch
Journal:  Immunogenetics       Date:  1986       Impact factor: 2.846
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