Literature DB >> 3916735

Either one of the two yeast EF-1 alpha genes is required for cell viability.

P Cottrelle1, M Cool, P Thuriaux, V L Price, D Thiele, J M Buhler, P Fromageot.   

Abstract

Two genes, TEF1 and TEF2, encode the protein elongation factor EF-1 alpha in the yeast Saccharomyces cerevisiae. We have generated yeast haploid strains containing either TEF1 or TEF2 interrupted by insertion of a large piece of foreign DNA. Cells which contain either one functional copy of the EF-1 alpha genes are viable. In contrast, attempts to isolate a yeast haploid strain with both TEF1 and TEF2 inactivated have failed suggesting that the double gene disruption is a lethal event.

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Year:  1985        PMID: 3916735     DOI: 10.1007/bf00449823

Source DB:  PubMed          Journal:  Curr Genet        ISSN: 0172-8083            Impact factor:   3.886


  17 in total

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Authors:  R K Mortimer; D C Hawthorne
Journal:  Methods Cell Biol       Date:  1975       Impact factor: 1.441

2.  Detection of specific sequences among DNA fragments separated by gel electrophoresis.

Authors:  E M Southern
Journal:  J Mol Biol       Date:  1975-11-05       Impact factor: 5.469

3.  Cloning, nucleotide sequence, and expression of one of two genes coding for yeast elongation factor 1 alpha.

Authors:  P Cottrelle; D Thiele; V L Price; S Memet; J Y Micouin; C Marck; J M Buhler; A Sentenac; P Fromageot
Journal:  J Biol Chem       Date:  1985-03-10       Impact factor: 5.157

4.  Identification of two copies of the gene for the elongation factor EF-Tu in E. coli.

Authors:  S R Jaskunas; L Lindahl; M Nomura
Journal:  Nature       Date:  1975-10-09       Impact factor: 49.962

Review 5.  The elongation factor EF-Tu and its two encoding genes.

Authors:  L Bosch; B Kraal; P H Van der Meide; F J Duisterwinkel; J M Van Noort
Journal:  Prog Nucleic Acid Res Mol Biol       Date:  1983

6.  Lethal disruption of the yeast actin gene by integrative DNA transformation.

Authors:  D Shortle; J E Haber; D Botstein
Journal:  Science       Date:  1982-07-23       Impact factor: 47.728

7.  The elongation factor Tu coded by the tufA gene of Escherichia coli K-12 is almost identical to that coded by the tufB gene.

Authors:  A V Furano
Journal:  J Biol Chem       Date:  1977-03-25       Impact factor: 5.157

8.  High-frequency transformation of yeast: autonomous replication of hybrid DNA molecules.

Authors:  K Struhl; D T Stinchcomb; S Scherer; R W Davis
Journal:  Proc Natl Acad Sci U S A       Date:  1979-03       Impact factor: 11.205

9.  Conservation of high efficiency promoter sequences in Saccharomyces cerevisiae.

Authors:  M J Dobson; M F Tuite; N A Roberts; A J Kingsman; S M Kingsman; R E Perkins; S C Conroy; L A Fothergill
Journal:  Nucleic Acids Res       Date:  1982-04-24       Impact factor: 16.971

10.  Elongation factor 1 alpha from Saccharomyces cerevisiae. Rapid large-scale purification and molecular characterization.

Authors:  D Thiele; P Cottrelle; F Iborra; J M Buhler; A Sentenac; P Fromageot
Journal:  J Biol Chem       Date:  1985-03-10       Impact factor: 5.157

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  15 in total

1.  eEF1A Controls ascospore differentiation through elevated accuracy, but controls longevity and fruiting body formation through another mechanism in Podospora anserina.

Authors:  P Silar; H Lalucque; V Haedens; D Zickler; M Picard
Journal:  Genetics       Date:  2001-08       Impact factor: 4.562

2.  Elongation factor EF-1 alpha gene dosage alters translational fidelity in Saccharomyces cerevisiae.

Authors:  J M Song; S Picologlou; C M Grant; M Firoozan; M F Tuite; S Liebman
Journal:  Mol Cell Biol       Date:  1989-10       Impact factor: 4.272

3.  Developmental analysis of elongation factor-1 alpha expression in transgenic tobacco.

Authors:  V M Ursin; J M Irvine; W R Hiatt; C K Shewmaker
Journal:  Plant Cell       Date:  1991-06       Impact factor: 11.277

4.  Efficient transcription of the glycolytic gene ADH1 and three translational component genes requires the GCR1 product, which can act through TUF/GRF/RAP binding sites.

Authors:  G M Santangelo; J Tornow
Journal:  Mol Cell Biol       Date:  1990-02       Impact factor: 4.272

5.  Direct detection of viable bacteria, molds, and yeasts by reverse transcriptase PCR in contaminated milk samples after heat treatment.

Authors:  M Vaitilingom; F Gendre; P Brignon
Journal:  Appl Environ Microbiol       Date:  1998-03       Impact factor: 4.792

6.  The gene family encoding the Arabidopsis thaliana translation elongation factor EF-1 alpha: molecular cloning, characterization and expression.

Authors:  M Axelos; C Bardet; T Liboz; A Le Van Thai; C Curie; B Lescure
Journal:  Mol Gen Genet       Date:  1989-10

7.  Elongation factor 1 alpha genes of the red alga Porphyra purpurea include a novel, developmentally specialized variant.

Authors:  Q Y Liu; S L Baldauf; M E Reith
Journal:  Plant Mol Biol       Date:  1996-04       Impact factor: 4.076

8.  Biphasic Stimulation of Translational Activity Correlates with Induction of Translation Elongation Factor 1 Subunit [alpha] upon Wounding in Potato Tubers.

Authors:  J. K. Morelli; C. K. Shewmaker; M. E. Vayda
Journal:  Plant Physiol       Date:  1994-11       Impact factor: 8.340

9.  Damaging de novo missense variants in EEF1A2 lead to a developmental and degenerative epileptic-dyskinetic encephalopathy.

Authors:  Gemma L Carvill; Katherine L Helbig; Candace T Myers; Marcello Scala; Robert Huether; Sara Lewis; Tyler N Kruer; Brandon S Guida; Somayeh Bakhtiari; Joy Sebe; Sha Tang; Heather Stickney; Sehribani Ulusoy Oktay; Ashwin A Bhandiwad; Keri Ramsey; Vinodh Narayanan; Timothy Feyma; Luis O Rohena; Andrea Accogli; Mariasavina Severino; Georgina Hollingsworth; Deepak Gill; Christel Depienne; Caroline Nava; Lynette G Sadleir; Paul A Caruso; Angela E Lin; Floor E Jansen; Bobby Koeleman; Eva Brilstra; Marjolein H Willemsen; Tjitske Kleefstra; Joaquim Sa; Marie-Laure Mathieu; Laurine Perrin; Gaetan Lesca; Pasquale Striano; Giorgio Casari; Ingrid E Scheffer; David Raible; Evelyn Sattlegger; Valeria Capra; Sergio Padilla-Lopez; Heather C Mefford; Michael C Kruer
Journal:  Hum Mutat       Date:  2020-04-06       Impact factor: 4.878

10.  A comprehensive compilation of 1001 nucleotide sequences coding for proteins from the yeast Saccharomyces cerevisiae (= ListA2)

Authors:  M O Mossé; P Linder; J Lazowska; P P Slonimski
Journal:  Curr Genet       Date:  1993-01       Impact factor: 3.886

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