Literature DB >> 3916719

UV-induced instability in Candida albicans hybrids.

W L Whelan1, D Markie.   

Abstract

Auxotrophic variants were obtained following UV-irradiation of Candida albicans hybrids which were heterozygous (+/+/-/-/) for various genetic markers (met, ade, his, lys). Some variants contained less DNA (per cell) than did the hybrids from which they originated; such variants were considered to arise in a process which resulted in generalized reduction in ploidy. These results provide the basis for a cyclic parasexual system (2n X 2n----4n----2n) for genetic analysis in this amictic diploid species.

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Year:  1985        PMID: 3916719     DOI: 10.1007/bf00436967

Source DB:  PubMed          Journal:  Curr Genet        ISSN: 0172-8083            Impact factor:   3.886


  8 in total

1.  A genetic analysis of Candida albicans: isolation of a wide variety of auxotrophs and demonstration of linkage and complementation.

Authors:  S N Kakar; R M Partridge; P T Magee
Journal:  Genetics       Date:  1983-06       Impact factor: 4.562

2.  Selection and fusion of auxotrophic protoplasts of Candida albicans.

Authors:  K O Evans; A Adeniji; D O McClary
Journal:  Antonie Van Leeuwenhoek       Date:  1982-05       Impact factor: 2.271

3.  DNA content, kinetic complexity, and the ploidy question in Candida albicans.

Authors:  W S Riggsby; L J Torres-Bauza; J W Wills; T M Townes
Journal:  Mol Cell Biol       Date:  1982-07       Impact factor: 4.272

4.  Heterozygosity and segregation in Candida albicans.

Authors:  W L Whelan; R M Partridge; P T Magee
Journal:  Mol Gen Genet       Date:  1980

5.  Parasexual genetic analysis of Candida albicans by spheroplast fusion.

Authors:  R Poulter; K Jeffery; M J Hubbard; M G Shepherd; P A Sullivan
Journal:  J Bacteriol       Date:  1981-06       Impact factor: 3.490

6.  Hybridization of Candida albicans through fusion of protoplasts.

Authors:  A Sarachek; D D Rhoads; R H Schwarzhoff
Journal:  Arch Microbiol       Date:  1981-03       Impact factor: 2.552

7.  Genetic analysis of red, adenine-requiring mutants of Candida albicans.

Authors:  R T Poulter; E H Rikkerink
Journal:  J Bacteriol       Date:  1983-12       Impact factor: 3.490

8.  Recombination analysis of naturally diploid Candida albicans.

Authors:  R Poulter; V Hanrahan; K Jeffery; D Markie; M G Shepherd; P A Sullivan
Journal:  J Bacteriol       Date:  1982-12       Impact factor: 3.490

  8 in total
  3 in total

1.  Complementation analysis of resistance to 5-fluorocytosine in Candida albicans.

Authors:  W L Whelan; D Markie; K J Kwon-Chung
Journal:  Antimicrob Agents Chemother       Date:  1986-05       Impact factor: 5.191

2.  Genetic differences between type I and type II Candida stellatoidea.

Authors:  K J Kwon-Chung; W S Riggsby; R A Uphoff; J B Hicks; W L Whelan; E Reiss; B B Magee; B L Wickes
Journal:  Infect Immun       Date:  1989-02       Impact factor: 3.441

3.  Analysis of Repair Mechanisms following an Induced Double-Strand Break Uncovers Recessive Deleterious Alleles in the Candida albicans Diploid Genome.

Authors:  Adeline Feri; Raphaël Loll-Krippleber; Pierre-Henri Commere; Corinne Maufrais; Natacha Sertour; Katja Schwartz; Gavin Sherlock; Marie-Elisabeth Bougnoux; Christophe d'Enfert; Mélanie Legrand
Journal:  MBio       Date:  2016-10-11       Impact factor: 7.867

  3 in total

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