| Literature DB >> 3916719 |
Abstract
Auxotrophic variants were obtained following UV-irradiation of Candida albicans hybrids which were heterozygous (+/+/-/-/) for various genetic markers (met, ade, his, lys). Some variants contained less DNA (per cell) than did the hybrids from which they originated; such variants were considered to arise in a process which resulted in generalized reduction in ploidy. These results provide the basis for a cyclic parasexual system (2n X 2n----4n----2n) for genetic analysis in this amictic diploid species.Entities:
Mesh:
Substances:
Year: 1985 PMID: 3916719 DOI: 10.1007/bf00436967
Source DB: PubMed Journal: Curr Genet ISSN: 0172-8083 Impact factor: 3.886