Literature DB >> 3907275

The influence of purified somatomedins and insulin on foetal rat brain DNA synthesis in vitro.

G Enberg, A Tham, V R Sara.   

Abstract

The two main forms of somatomedins, termed insulin-like growth factor I and II (IGF-I and IGF-II), have been isolated from human plasma. Pure IGF-I or IGF-II was incubated with foetal rat brain cells and found to be equipotent in stimulating the [3H]thymidine incorporation into DNA, despite the fact that IGF-I not is present during foetal life.

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Year:  1985        PMID： 3907275     DOI： 10.1111/j.1748-1716.1985.tb07720.x

Source DB:  PubMed          Journal:  Acta Physiol Scand        ISSN： 0001-6772


  6 in total

Review 1.  Molecular biology of the insulin-like growth factors. Relevance to nervous system function.

Authors:  J E Hepler; P K Lund
Journal:  Mol Neurobiol       Date:  1990 Spring-Summer       Impact factor: 5.590

2.  Expression of the insulin-like growth factor II gene in the choroid plexus and the leptomeninges of the adult rat central nervous system.

Authors:  F Stylianopoulou; J Herbert; M B Soares; A Efstratiadis
Journal:  Proc Natl Acad Sci U S A       Date:  1988-01       Impact factor: 11.205

3.  Fibroblast growth factor-mediated proliferation of central nervous system precursors depends on endogenous production of insulin-like growth factor I.

Authors:  J Drago; M Murphy; S M Carroll; R P Harvey; P F Bartlett
Journal:  Proc Natl Acad Sci U S A       Date:  1991-03-15       Impact factor: 11.205

4.  Characterization of somatomedins from human fetal brain: identification of a variant form of insulin-like growth factor I.

Authors:  V R Sara; C Carlsson-Skwirut; C Andersson; E Hall; B Sjögren; A Holmgren; H Jörnvall
Journal:  Proc Natl Acad Sci U S A       Date:  1986-07       Impact factor: 11.205

5.  Regulation of insulin-like growth factor II receptors by growth hormone and insulin in rat adipocytes.

Authors:  P Lönnroth; K Assmundsson; S Edén; G Enberg; I Gause; K Hall; U Smith
Journal:  Proc Natl Acad Sci U S A       Date:  1987-06       Impact factor: 11.205

6.  Insulin growth factors regulate the mitotic cycle in cultured rat sympathetic neuroblasts.

Authors:  E DiCicco-Bloom; I B Black
Journal:  Proc Natl Acad Sci U S A       Date:  1988-06       Impact factor: 11.205
  6 in total

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