| Literature DB >> 3905430 |
T S Emudianughe, Q D Bickle, M G Taylor, B Andrews.
Abstract
The metabolism of benzoic acid was studied in Plasmodium berghei infected mice both in vitro and in vivo. Results of in vitro studies showed a considerable decrease in the ability of the infected liver to detoxify benzoic acid by hippuric acid formation. The in vivo study showed that hippuric acid formation decreases with increasing parasitemia and the emergence of benzoyl-glucuronide. This new pathway stops operating with further increase in parasitemia.Entities:
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Year: 1985 PMID： 3905430 DOI： 10.1007/bf01950007
Source DB: PubMed Journal: Experientia ISSN： 0014-4754