Literature DB >> 3904690

Nerve fibres containing peptide histidine isoleucine (PHI) in the respiratory tract.

R Uddman, A Luts, F Sundler.   

Abstract

Recent studies have indicated that vasoactive intestinal peptide (VIP) and peptide histidine isoleucine (PHI) are formed by cleavage of a common precursor protein. In the present study we have examined the distribution of nerve fibres displaying PHI-like immunoreactivity in the upper respiratory tract of several mammalian species including man. PHI fibres were found to have the same general distribution as previously described for VIP fibres. These fibres were distributed mainly in the subepithelial connective tissue around both seromucous glands and blood vessels. In the tracheal wall, PHI fibres were also seen in the non-vascular smooth muscle. Sequential immunostaining for PHI and VIP revealed co-existence of the two peptides in the same nerve fibres.

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Year:  1985        PMID： 3904690     DOI： 10.1007/bf00454420

Source DB:  PubMed          Journal:  Arch Otorhinolaryngol        ISSN： 0302-9530


  12 in total

1.  Identification and processing of biosynthetic precursors to vasoactive intestinal polypeptide in human neuroblastoma cells.

Authors:  K Obata; N Itoh; H Okamoto; C Yanaihara; N Yanaihara; T Suzuki
Journal:  FEBS Lett       Date:  1981-12-21       Impact factor: 4.124

2.  Distribution of peptide histidine isoleucine in the mammalian respiratory tract and some aspects of its pharmacology.

Authors:  N D Christofides; Y Yiangou; P J Piper; M A Ghatei; M N Sheppard; K Tatemoto; J M Polak; S R Bloom
Journal:  Endocrinology       Date:  1984-11       Impact factor: 4.736

3.  Radioimmunoassay and intramural distribution of PHI-IR in human intestine.

Authors:  N D Christofides; Y Yiangou; E Aarons; G L Ferri; K Tatemoto; J M Polak; S R Bloom
Journal:  Dig Dis Sci       Date:  1983-06       Impact factor: 3.199

4.  Occurrence and distribution of GRP-immunoreactive nerve fibres in the respiratory tract.

Authors:  R Uddman; E Moghimzadeh; F Sundler
Journal:  Arch Otorhinolaryngol       Date:  1984

5.  Human preprovasoactive intestinal polypeptide contains a novel PHI-27-like peptide, PHM-27.

Authors:  N Itoh; K Obata; N Yanaihara; H Okamoto
Journal:  Nature       Date:  1983 Aug 11-17       Impact factor: 49.962

6.  Occurrence and distribution of VIP nerves in the nasal mucosa and tracheobronchial wall.

Authors:  R Uddman; J Alumets; O Densert; R Håkanson; F Sundler
Journal:  Acta Otolaryngol       Date:  1978 Nov-Dec       Impact factor: 1.494

7.  Occurrence and distribution of neuropeptide-Y-immunoreactive nerves in the respiratory tract and middle ear.

Authors:  R Uddman; F Sundler; P Emson
Journal:  Cell Tissue Res       Date:  1984       Impact factor: 5.249

8.  Substance-P-containing nerve fibers in the nasal mucosa.

Authors:  R Uddman; L Malm; F Sundler
Journal:  Arch Otorhinolaryngol       Date:  1983

9.  Isolation and characterization of the intestinal peptide porcine PHI (PHI-27), a new member of the glucagon--secretin family.

Authors:  K Tatemoto; V Mutt
Journal:  Proc Natl Acad Sci U S A       Date:  1981-11       Impact factor: 11.205

10.  Studies on antibody production. I. A method for the histochemical demonstration of specific antibody and its application to a study of the hyperimmune rabbit.

Authors:  A H COONS; E H LEDUC; J M CONNOLLY
Journal:  J Exp Med       Date:  1955-07-01       Impact factor: 14.307
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  1 in total

1.  Pituitary adenylate cyclase-activating peptide (PACAP), a new vasoactive intestinal peptide (VIP)-like peptide in the respiratory tract.

Authors:  R Uddman; A Luts; A Arimura; F Sundler
Journal:  Cell Tissue Res       Date:  1991-07       Impact factor: 5.249
  1 in total

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