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Literature DB >> 3903746

Immunological detection of hemoglobin in bones of ancient Roman times and of Iron and Eneolithic Ages.

Abstract

Using an immunological method (immunoblot), we have established that hemoglobin (or hemoglobin fragments) can be quantitatively determined in old and ancient bones, some of them dating back 4500 years. It is shown that the total recovery decreases with time, but it is still effective in the older specimens. Thus, the immunological assay may prove useful to solve problems relevant to paleontology and paleopathology.

Entities: Chemical

Mesh：

Substances：

Year: 1985 PMID： 3903746 PMCID： PMC390810 DOI： 10.1073/pnas.82.21.7170

Source DB: PubMed Journal: Proc Natl Acad Sci U S A ISSN： 0027-8424 Impact factor: 11.205

6 in total

1. A problem in palaeopathology. The origin of thalassemia in Italy.

Authors: A Ascenzi
Journal: Virchows Arch A Pathol Anat Histol Date: 1979

2. Imbalanced globin chain synthesis in heterozygous beta-thalassemic bone marrow.

Authors: G Chalevelakis; J B Clegg; D J Weatherall
Journal: Proc Natl Acad Sci U S A Date: 1975-10 Impact factor: 11.205

Review 3. Regulation of oxygen affinity of hemoglobin: influence of structure of the globin on the heme iron.

Authors: M F Perutz
Journal: Annu Rev Biochem Date: 1979 Impact factor: 23.643

4. A novel and comprehensive synthetic approach for the elucidation of protein antigenic structures. Determination of the full antigenic profile of the alpha-chain of human haemoglobin.

Authors: A L Kazim; M Z Atassi
Journal: Biochem J Date: 1980-10-01 Impact factor: 3.857

5. A dot-immunobinding assay for monoclonal and other antibodies.

Authors: R Hawkes; E Niday; J Gordon
Journal: Anal Biochem Date: 1982-01-01 Impact factor: 3.365

6. Some immunochemical properties of Pseudomonas aeruginosa cytochrome oxidase (or nitrate reductase).

Authors: M C Silvestrini; A Colosimo; M Brunori; G Citro; R Zito
Journal: FEBS Lett Date: 1980-04-21 Impact factor: 4.124

6 in total

4 in total

Immunological detection of hemoglobin in bones of ancient Roman times and of Iron and Eneolithic Ages.

1. A problem in palaeopathology. The origin of thalassemia in Italy.

2. Imbalanced globin chain synthesis in heterozygous beta-thalassemic bone marrow.

Review 3. Regulation of oxygen affinity of hemoglobin: influence of structure of the globin on the heme iron.

4. A novel and comprehensive synthetic approach for the elucidation of protein antigenic structures. Determination of the full antigenic profile of the alpha-chain of human haemoglobin.

5. A dot-immunobinding assay for monoclonal and other antibodies.

6. Some immunochemical properties of Pseudomonas aeruginosa cytochrome oxidase (or nitrate reductase).

1. Adaptative value of a PKC-PKI55 feedback loop of inhibition that prevents the kinase's deregulation.

2. Immunology and art: using antibody-based techniques to identify proteins and gums in artworks.

3. Heme compounds in dinosaur trabecular bone.

4. Proteomic profiling of archaeological human bone.