| Literature DB >> 390307 |
H Sommer, J Cullum, H Saedler.
Abstract
The sequence of two new IS2 alleles with promoter activity (IS2-43 and IS2-44) is reported. The alleles are identical and are formed by a 17 bp tandem duplication in an AT-rich region of IS2. This created a new RNA polymerase binding site. A mutation was found that increased the frequency of formation of these 17 bp duplications but not of another class of duplications, the "mini-insertions". This suggested that the mechanisms of formation of the two classes of duplications are different.Entities:
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Year: 1979 PMID: 390307 DOI: 10.1007/bf00267855
Source DB: PubMed Journal: Mol Gen Genet ISSN: 0026-8925