| Literature DB >> 3900283 |
J León, J M García-Lobo, J Navas, J M Ortiz.
Abstract
Escherichia coli cells carrying fosfomycin-resistance plasmids modify fosfomycin intracellularly. The product of this modification (fosfomycin-derivative) differs from fosfomycin in chromatographic mobility, but the chemical nature of the modification is not yet known. Fosfomycin-derivative appears to have a cytoplasmic location and lacks antibiotic activity. The modification system can be saturated by an excess of fosfomycin in the incubation media.Entities:
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Year: 1985 PMID： 3900283 DOI： 10.1099/00221287-131-7-1649
Source DB: PubMed Journal: J Gen Microbiol ISSN： 0022-1287