Literature DB >> 3899508

pH-dependent processes in proteins.

J B Matthew, F R Gurd, B Garcia-Moreno, M A Flanagan, K L March, S J Shire.   

Abstract

Recent improvements in the understanding of electrostatic interactions in proteins serve as a focus for the general topic of pH-dependent processes in proteins. The general importance of pH-dependent processes is first set out in terms of hydrogen ion equilibria, stability, ligand interactions, assembly, dynamics, and events in related molecular systems. The development of various theoretical treatments includes various formalisms in addition to the solvent interface model developed by Shire et al. as an extension of the Tanford-Kirkwood treatment. A number of detailed applications of the model are presented and future potentialities are sketched.

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Year:  1985        PMID： 3899508     DOI： 10.3109/10409238509085133

Source DB:  PubMed          Journal:  CRC Crit Rev Biochem        ISSN： 0045-6411


  48 in total

1.  Thermodynamic linkage between the binding of protons and inhibitors to HIV-1 protease.

Authors:  J Trylska; J Antosiewicz; M Geller; C N Hodge; R M Klabe; M S Head; M K Gilson
Journal:  Protein Sci       Date:  1999-01       Impact factor: 6.725

2.  Distance dependence and salt sensitivity of pairwise, coulombic interactions in a protein.

Authors:  Kelly K Lee; Carolyn A Fitch; Bertrand García-Moreno E
Journal:  Protein Sci       Date:  2002-05       Impact factor: 6.725

3.  In silico investigation of pH-dependence of prolactin and human growth hormone binding to human prolactin receptor.

Authors:  Lin Wang; Shawn Witham; Zhe Zhang; Lin Li; Michael E Hodsdon; Emil Alexov
Journal:  Commun Comput Phys       Date:  2013-01       Impact factor: 3.246

Review 4.  Progress in the prediction of pKa values in proteins.

Authors:  Emil Alexov; Ernest L Mehler; Nathan Baker; António M Baptista; Yong Huang; Francesca Milletti; Jens Erik Nielsen; Damien Farrell; Tommy Carstensen; Mats H M Olsson; Jana K Shen; Jim Warwicker; Sarah Williams; J Michael Word
Journal:  Proteins       Date:  2011-10-15

Review 5.  The pKa Cooperative: a collaborative effort to advance structure-based calculations of pKa values and electrostatic effects in proteins.

Authors:  Jens E Nielsen; M R Gunner; Bertrand E García-Moreno
Journal:  Proteins       Date:  2011-10-15

6.  Local conformational fluctuations can modulate the coupling between proton binding and global structural transitions in proteins.

Authors:  Steven T Whitten; Bertrand García-Moreno E; Vincent J Hilser
Journal:  Proc Natl Acad Sci U S A       Date:  2005-03-14       Impact factor: 11.205

7.  pK values of the ionizable groups of proteins.

Authors:  Richard L Thurlkill; Gerald R Grimsley; J Martin Scholtz; C Nick Pace
Journal:  Protein Sci       Date:  2006-04-05       Impact factor: 6.725

8.  Electrostatic interactions modulate the conformation of collagen I.

Authors:  Uwe Freudenberg; Sven H Behrens; Petra B Welzel; Martin Müller; Milauscha Grimmer; Katrin Salchert; Tilman Taeger; Kati Schmidt; Wolfgang Pompe; Carsten Werner
Journal:  Biophys J       Date:  2007-01-05       Impact factor: 4.033

9.  In silico modeling of pH-optimum of protein-protein binding.

Authors:  Rooplekha C Mitra; Zhe Zhang; Emil Alexov
Journal:  Proteins       Date:  2010-12-22

10.  Computational design of the Fyn SH3 domain with increased stability through optimization of surface charge charge interactions.

Authors:  Katrina L Schweiker; Arash Zarrine-Afsar; Alan R Davidson; George I Makhatadze
Journal:  Protein Sci       Date:  2007-12       Impact factor: 6.725
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