| Literature DB >> 3899189 |
Abstract
The RecA protein of Escherichia coli plays a central role in DNA repair mechanisms. When it is incubated with single-stranded DNA and a nucleoside triphosphate, the purified RecA protein acts both by promoting cleavage of the LexA protein, the repressor of the SOS genes, and by catalyzing strand exchange between a variety of DNA molecules. A model for the regulation of the activity of the RecA protein in a cell exposed to a DNA damaging treatment is proposed.Entities:
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Year: 1985 PMID： 3899189 DOI： 10.1016/s0300-9084(85)80079-1
Source DB: PubMed Journal: Biochimie ISSN： 0300-9084 Impact factor: 4.079