| Literature DB >> 3895435 |
L H Van der Ploeg, M Smits, T Ponnudurai, A Vermeulen, J H Meuwissen, G Langsley.
Abstract
At least seven chromosome-sized DNA molecules (750 to 2000 kilobases in length and one fraction of undetermined molecular weight) from cultured clones and isolates of Plasmodium falciparum have been separated by pulsed-field gradient gel electrophoresis. Whereas asexual blood stages and sexual stages of the same line have identical molecular karyotypes, the length of chromosome-sized DNA molecules among different geographical isolates and several clones derived from a single patient is different. These length alterations of chromosomes are the result of DNA rearrangements that must occur unrelated to sexual differentiation.Entities:
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Year: 1985 PMID: 3895435 DOI: 10.1126/science.3895435
Source DB: PubMed Journal: Science ISSN: 0036-8075 Impact factor: 47.728