Literature DB >> 3894216

Butoconazole and miconazole in treating vaginal candidiasis.

C S Bradbeer, S R Mayhew, D Barlow.   

Abstract

In a single blind trial, a three day course of butoconazole nitrate cream was compared with a seven day course of miconazole nitrate cream, both applied intravaginally, in treating vaginal candidiasis. They were equally effective. The cure rate for patients treated with butoconazole was 82.8% at the first follow up (a mean of 18.4 days from the beginning of the treatment) and 76.7% at second follow up (a mean of 40.4 days). Cure rates for patients treated with miconazole were 84.4% and 75.8% respectively. The differences between these cure rates were not significant.

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Year:  1985        PMID: 3894216      PMCID: PMC1011829          DOI: 10.1136/sti.61.4.270

Source DB:  PubMed          Journal:  Genitourin Med        ISSN: 0266-4348


  3 in total

1.  1-[4-(4-Chlorophenyl)-2-(2,6-dichlorophenylthio)-n-butyl]-1H-imidazole nitrate, a new potent antifungal agent.

Authors:  K A Walker; A C Braemer; S Hitt; R E Jones; T R Matthews
Journal:  J Med Chem       Date:  1978-08       Impact factor: 7.446

2.  Clotrimazole and econazole in the treatment of vaginal candidosis. A single-blind comparison.

Authors:  G Gabriel; R N Thin
Journal:  Br J Vener Dis       Date:  1983-02

3.  A comparison between the effects of nystatin, clotrimazole and miconazole on vaginal candidiasis.

Authors:  B W Eliot; R C Howat; A E Mack
Journal:  Br J Obstet Gynaecol       Date:  1979-07
  3 in total
  5 in total

Review 1.  An overview of topical antifungal therapy in dermatomycoses. A North American perspective.

Authors:  A K Gupta; T R Einarson; R C Summerbell; N H Shear
Journal:  Drugs       Date:  1998-05       Impact factor: 9.546

Review 2.  Overview of medically important antifungal azole derivatives.

Authors:  R A Fromtling
Journal:  Clin Microbiol Rev       Date:  1988-04       Impact factor: 26.132

Review 3.  Candidiasis (vulvovaginal).

Authors:  Des Spence
Journal:  BMJ Clin Evid       Date:  2010-01-05

Review 4.  Candidiasis (vulvovaginal).

Authors:  Juliana Ester Martin Lopez
Journal:  BMJ Clin Evid       Date:  2015-03-16

5.  Development of a liquid chromatography-tandem mass spectrometry method for determination of butoconazole nitrate in human plasma and its application to a pharmacokinetic study.

Authors:  Meng-Meng Jia; Ying Zhou; Xiao-Meng He; Yi-Lai Wu; Hu-Qun Li; Hui Chen; Wei-Yong Li
Journal:  J Huazhong Univ Sci Technolog Med Sci       Date:  2014-06-18
  5 in total

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