| Literature DB >> 357722 |
K A Walker, A C Braemer, S Hitt, R E Jones, T R Matthews.
Abstract
The preparation and antifungal properties of 1-[4-(4-chlorophenyl)-2-(2,6-dichlorophenylthio)-n-butyl]-1H-imidazole nitrate 1 are described. It is particularly effective against in vivo Candida albicans infections (mice), maintaining good activity down to 0.25% formulation strength and showing unusually low reinfection rates after treatment is ended.Entities:
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Year: 1978 PMID： 357722 DOI： 10.1021/jm00206a028
Source DB: PubMed Journal: J Med Chem ISSN： 0022-2623 Impact factor: 7.446