| Literature DB >> 3891418 |
Abstract
A family of functionally important, high-molecular-weight glycoproteins with identical beta subunits has recently been defined on leukocyte cell surfaces. Soon after these molecules and at least some of their functions had been defined with monoclonal antibodies, an inherited disease, LFA-1, Mac-1 deficiency, was discovered in humans. This deficiency has confirmed that this glycoprotein family is of central importance in leukocyte cell surface adhesion reactions.Entities:
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Year: 1985 PMID: 3891418
Source DB: PubMed Journal: Fed Proc ISSN: 0014-9446