Literature DB >> 3887150

Assembly and preliminary analysis of a genotoxicity data base for predicting carcinogens.

M Palajda, H S Rosenkranz.   

Abstract

With a view to developing methodologies for predicting the carcinogenicity of chemicals on the basis of the results of short-term assays and selecting highly predictive batteries of short-term tests, a data base was assembled. The present is a compilation of data extracted from the reports of Gene-Tox working groups, Salmonella mutagenicity data obtained from the U.S. National Toxicology Program and the Environmental Mutagen Information Center and results from BHK21 transformation assays.

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Year:  1985        PMID: 3887150     DOI: 10.1016/0165-1110(85)90010-7

Source DB:  PubMed          Journal:  Mutat Res        ISSN: 0027-5107            Impact factor:   2.433


  4 in total

Review 1.  Invited contribution: an objective approach to the development of short-term tests predictive of carcinogenicity.

Authors:  H S Rosenkranz; F K Ennever; V Chankong; J Pet-Edwards; Y Y Haimes
Journal:  Cell Biol Toxicol       Date:  1986-12       Impact factor: 6.691

2.  Predicting mammalian mutagenesis by submammalian assays: an application of database GEN.

Authors:  F E Würgler
Journal:  Environ Health Perspect       Date:  1991-12       Impact factor: 9.031

3.  Mathematical models for exploring different aspects of genotoxicity and carcinogenicity databases.

Authors:  R Benigni; A Giuliani
Journal:  Environ Health Perspect       Date:  1991-12       Impact factor: 9.031

4.  Quantitative predictability of carcinogenicity of the covalent binding index of chemicals to DNA: comparison of the in vivo and in vitro assays.

Authors:  M Taningher; G Saccomanno; L Santi; S Grilli; S Parodi
Journal:  Environ Health Perspect       Date:  1990-03       Impact factor: 9.031

  4 in total

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