Literature DB >> 388714

Theophylline-7-acetic acid: lack of absorption and therapeutic effectiveness.

J A Fleetham, J A Owen, B May, P W Munt, K Nakatsu.   

Abstract

A double-blind cross-over trial was conducted to evaluate the effectiveness of oral theophylline-7-acetic acid (T7AA) in 13 asthmatic patients. Pulmonary function tests showed no difference between T7AA and placebo. No T7AA or theophylline was found in the sera of these patients or of healthy volunteers who took T7AA tablets or syrup.

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Year:  1979        PMID: 388714      PMCID: PMC471113          DOI: 10.1136/thx.34.4.540

Source DB:  PubMed          Journal:  Thorax        ISSN: 0040-6376            Impact factor:   9.139


  7 in total

1.  Dosage of theophylline in bronchial asthma.

Authors:  K M Piafsky; R I Ogilvie
Journal:  N Engl J Med       Date:  1975-06-05       Impact factor: 91.245

2.  An objective comparison of two recent neutral theophylline compounds with aminophylline.

Authors:  D N PHEAR
Journal:  Br Med J       Date:  1957-07-13

3.  Absorption and excretion of piperazine theophylline ethanoate- 14 C in the rat.

Authors:  M Strolin-Benedetti; D A Larue; C Oliver; P Bouvet
Journal:  Arzneimittelforschung       Date:  1971-05

4.  Assessment of lung function using an air-flow meter.

Authors:  M Friedman; S Walker
Journal:  Lancet       Date:  1975-02-08       Impact factor: 79.321

5.  Spectrophotometry of theophylline-7-acetic acid and theophylline.

Authors:  J A Owen; K Nakatsu
Journal:  Clin Chem       Date:  1978-02       Impact factor: 8.327

6.  Is acephylline a theophylline bronchodilator?

Authors:  J Zuidema; F W Merkus
Journal:  Lancet       Date:  1978-06-17       Impact factor: 79.321

7.  Reliable fifteen-minute assay for theophylline.

Authors:  K Nakatsu; J A Owen; K Scully
Journal:  Clin Biochem       Date:  1978-08       Impact factor: 3.281

  7 in total

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