Literature DB >> 388135

Identification of ergosta-8,24(28)-dien-3 beta,6 alpha-diol in A delta 8 goes to delta 7 sterol isomerase-blocked yeast mutant.

A M Pierce, H D Pierce, A M Unrau, A C Oehlschlager, R A Woods.   

Abstract

In addition to the monohydroxysterols found in the delta 8 goes to delta 7 isomerase-blocked Saccharomyces cerevisiae mutant erg 2, a noval dihydroxysterol, ergosta-8,24(38)-dien-3 beta,6 alpha-diol, was isolated. This sterol accumulated to the extent of 2.1% of the total sterol fraction when this mutant was treated with 23-azacholesterol, a known inhibitor of the 24-methylene-sterol-24(28)-reductase.

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Year:  1979        PMID： 388135     DOI： 10.1007/bf02534132

Source DB:  PubMed          Journal:  Lipids        ISSN： 0024-4201            Impact factor:   1.880


  8 in total

1.  Lipid composition and polyene antibiotic resistance of Candida albicans mutants.

Authors:  A M Pierce; H D Pierce; A M Unrau; A C Oehlschlager
Journal:  Can J Biochem       Date:  1978-02

2.  Polyene resistance and the isolation of sterol mutants in Saccharomyces cerevisiae.

Authors:  S W Molzahn; R A Woods
Journal:  J Gen Microbiol       Date:  1972-09

3.  Formation of a 5 hydroxy sterol by Saccharomyces cerevisiae.

Authors:  M Fryberg; A C Oehlschlager; A M Unrau
Journal:  Biochem Biophys Res Commun       Date:  1973-03-05       Impact factor: 3.575

4.  Investigations on the biosynthesis of steroids and terpenoids. VI. The sterols of yeast.

Authors:  D H Barton; U M Kempe; D A Widdowson
Journal:  J Chem Soc Perkin 1       Date:  1972

5.  Azasterol inhibitors in yeast. Inhibition of the delta 24-sterol methyltransferase and the 24-methylene sterol delta 24(28)-reductase in sterol mutants of Saccharomyces cerevisiae.

Authors:  A M Pierce; A M Unrau; A C Oehlschlager; R A Woods
Journal:  Can J Biochem       Date:  1979-03

6.  Azasterol inhibitors in yeast. Inhibition of the 24-methylene sterol delta24(28)-reductase and delta24-sterol methyltransferase of Saccharomyces cerevisiae by 23-azacholesterol.

Authors:  H D Pierce; A M Pierce; R Srinivasan; A M Unrau; A C Oehlschlager
Journal:  Biochim Biophys Acta       Date:  1978-06-23

7.  Biological activity of some oxygenated sterols.

Authors:  A A Kandutsch; H W Chen; H J Heiniger
Journal:  Science       Date:  1978-08-11       Impact factor: 47.728

8.  Sterol mutants of Saccharomyces cerevisiae: chromatographic analyses.

Authors:  M Bard; R A Woods; D H Bartón; J E Corrie; D A Widdowson
Journal:  Lipids       Date:  1977-08       Impact factor: 1.880
  8 in total
  1 in total

1.  Induction of petite yeast mutants by membrane-active agents.

Authors:  J Jiménez; E Longo; T Benítez
Journal:  Appl Environ Microbiol       Date:  1988-12       Impact factor: 4.792
  1 in total

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