Literature DB >> 331007

Sterol mutants of Saccharomyces cerevisiae: chromatographic analyses.

M Bard, R A Woods, D H Bartón, J E Corrie, D A Widdowson.   

Abstract

The sterols accumulated by ergosterol deficient mutants of the genes erg6, erg2, erg3, and erg5 (formerly po11, po12, po13, and po15) have been analyzed by gas liquid chromatography. Together with pure sterols obtained from the mutants, they were characterized on SE-30, OV-17, and OV-225. The effects of molecular structure on the retention characteristics of a range of C28 ergostane sterols have been studied. The double mutants obtained by crossing the single mutants were also analyzed and their sterols identified where possible. The effects of the erg mutations on the control of sterol biosynthesis in yeast are discussed.

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Year:  1977        PMID： 331007     DOI： 10.1007/bf02533759

Source DB:  PubMed          Journal:  Lipids        ISSN： 0024-4201            Impact factor:   1.880


  18 in total

1.  Biosynthesis of terpenes and steroids. X. The sterols of some yeast mutants doubly defective in ergosterol biosynthesis.

Authors:  D H Barton; A A Gunatilaka; T R Jarman; D A Widdowson; M Bard; R A Woods
Journal:  J Chem Soc Perkin 1       Date:  1975

2.  Attempted induction of microbial mutants requiring steroidal growth factors.

Authors:  E A ADELBERG; P F ROSLANSKY; J W MYERS; C A COUGHLIN
Journal:  J Bacteriol       Date:  1955-06       Impact factor: 3.490

3.  Yeast mutant requiring only a sterol as growth supplement.

Authors:  F Karst; F Lacroute
Journal:  Biochem Biophys Res Commun       Date:  1974-07-10       Impact factor: 3.575

4.  Isolation of pleiotropic yeast mutants requiring ergosterol for growth.

Authors:  F Karst; F Lacroute
Journal:  Biochem Biophys Res Commun       Date:  1973-06-08       Impact factor: 3.575

5.  Biosynthesis of ergosterol in yeast. Evidence for multiple pathways.

Authors:  M Fryberg; A C Oehlschlager; A M Unrau
Journal:  J Am Chem Soc       Date:  1973-08-22       Impact factor: 15.419

6.  Resistance to polyene antibiotics and correlated sterol changes in two isolates of Candida tropicalis from a patient with an amphotericin B-resistant funguria.

Authors:  R A Woods; M Bard; I E Jackson; D J Drutz
Journal:  J Infect Dis       Date:  1974-01       Impact factor: 5.226

7.  Studies on the accumulation of ergosterol and 24(28)-dehydroergosterol in 3 strains of Saccharomyces cerevisiae.

Authors:  R A Woods; M Bard; I E Gardner; S W Molzahn
Journal:  Microbios       Date:  1974 Jun-Jul

8.  Yeast mutants requiring ergosterol as only lipid supplement.

Authors:  E G Gollub; P Trocha; P K Liu; D B Sprinson
Journal:  Biochem Biophys Res Commun       Date:  1974-01-23       Impact factor: 3.575

9.  Investigation of an S-adenosylmethionine: delta 24-sterol methyltransferase in ergosterol biosynthesis in yeast. Specificity of sterol substrates and inhibitors.

Authors:  J T Moore; J L Gaylor
Journal:  J Biol Chem       Date:  1970-09-25       Impact factor: 5.157

10.  Studies on the biosynthesis of ergosterol in yeast. Formation of methylated intermediates.

Authors:  H Katsuki; K Bloch
Journal:  J Biol Chem       Date:  1967-01-25       Impact factor: 5.157
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  15 in total

1.  Dual effects of plant steroidal alkaloids on Saccharomyces cerevisiae.

Authors:  Veronika Simons; John P Morrissey; Maita Latijnhouwers; Michael Csukai; Adam Cleaver; Carol Yarrow; Anne Osbourn
Journal:  Antimicrob Agents Chemother       Date:  2006-08       Impact factor: 5.191

2.  Overlapping functions of the yeast oxysterol-binding protein homologues.

Authors:  C T Beh; L Cool; J Phillips; J Rine
Journal:  Genetics       Date:  2001-03       Impact factor: 4.562

3.  Sterols of Saccharomyces cerevisiae erg6 Knockout Mutant Expressing the Pneumocystis carinii S-Adenosylmethionine:Sterol C-24 Methyltransferase.

Authors:  Edna S Kaneshiro; Laura Q Johnston; Stephenson W Nkinin; Becky I Romero; José-Luis Giner
Journal:  J Eukaryot Microbiol       Date:  2014-10-16       Impact factor: 3.346

4.  Specific sterols required for the internalization step of endocytosis in yeast.

Authors:  A L Munn; A Heese-Peck; B J Stevenson; H Pichler; H Riezman
Journal:  Mol Biol Cell       Date:  1999-11       Impact factor: 4.138

5.  Isolation of sterol mutants inChlamydomonas reinhardi: Chromatographic analyses.

Authors:  M Bard; K J Wilson; R M Thompson
Journal:  Lipids       Date:  1978-08       Impact factor: 1.880

6.  Differences in crystal violet uptake and cation-induced death among yeast sterol mutants.

Authors:  M Bard; N D Lees; L S Burrows; F W Kleinhans
Journal:  J Bacteriol       Date:  1978-09       Impact factor: 3.490

7.  Sterol methylation in Saccharomyces cerevisiae.

Authors:  M T McCammon; M A Hartmann; C D Bottema; L W Parks
Journal:  J Bacteriol       Date:  1984-02       Impact factor: 3.490

8.  Metabolic interconversion of free sterols and steryl esters in Saccharomyces cerevisiae.

Authors:  F R Taylor; L W Parks
Journal:  J Bacteriol       Date:  1978-11       Impact factor: 3.490

9.  The effect of AY-9944 on yeast sterol and sterol ester metabolism.

Authors:  R Pereira; C E Holmlund; N Whittaker
Journal:  Lipids       Date:  1983-08       Impact factor: 1.880

10.  Identification of ergosta-8,24(28)-dien-3 beta,6 alpha-diol in A delta 8 goes to delta 7 sterol isomerase-blocked yeast mutant.

Authors:  A M Pierce; H D Pierce; A M Unrau; A C Oehlschlager; R A Woods
Journal:  Lipids       Date:  1979-10       Impact factor: 1.880
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