| Literature DB >> 3876950 |
H Jingami, N Mizuno, H Takahashi, S Shibahara, Y Furutani, H Imura, S Numa.
Abstract
DNA complementary to the rat hypothalamic mRNA coding for the corticotropin-releasing factor precursor (prepro-CRF) has been cloned by screening a cDNA library with a human genomic DNA probe. Nucleotide sequence analysis of the cloned cDNA has revealed that rat prepro-CRF consists of 187 amino acid residues including a putative signal peptide. The CRF and putative signal peptide regions are more highly conserved among rat, human and ovine prepro-CRF than is the cryptic portion.Entities:
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Year: 1985 PMID: 3876950 DOI: 10.1016/0014-5793(85)80994-7
Source DB: PubMed Journal: FEBS Lett ISSN: 0014-5793 Impact factor: 4.124