| Literature DB >> 3186733 |
Y Okawara1, S D Morley, L O Burzio, H Zwiers, K Lederis, D Richter.
Abstract
The sequence of a cDNA encoding the corticotropin-releasing factor precursor has been identified by screening lambda gt11 libraries constructed from poly(A)+ RNA of the hypothalamic region of the white sucker Catostomus commersoni brain with synthetic oligonucleotide probes deduced from the sequence of the rat corticotropin-releasing factor. The amino acid sequence of corticotropin-releasing factor of the sucker is strikingly conserved when compared to its counterpart from rat and differs only in two positions at the carboxyl terminus; in contrast, there is little similarity between their cryptic regions.Entities:
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Year: 1988 PMID: 3186733 PMCID: PMC282473 DOI: 10.1073/pnas.85.22.8439
Source DB: PubMed Journal: Proc Natl Acad Sci U S A ISSN: 0027-8424 Impact factor: 11.205