Literature DB >> 3875445

Antimicrobial susceptibility of Pneumocystis carinii in culture.

M S Bartlett, R Eichholtz, J W Smith.   

Abstract

Pneumocystis carinii from infected rats were cultured on infected WI-38 human lung fibroblasts. After cultures were established, medium was replaced by medium containing antimicrobials and supernate organisms counted at specified times. Results show that metronidazole had no effect, amphotericin B suppressed organisms at 5 but not 0.5 microgram/ml, and miconazole, chloroquine, trimethoprim-sulfamethoxazole, and pentamidine isethionate suppressed organisms at the concentrations tested.

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Year:  1985        PMID： 3875445     DOI： 10.1016/0732-8893(85)90076-8

Source DB:  PubMed          Journal:  Diagn Microbiol Infect Dis        ISSN： 0732-8893            Impact factor:   2.803


  25 in total

Review 1.  Antifungal agents: chemotherapeutic targets and immunologic strategies.

Authors:  N H Georgopapadakou; T J Walsh
Journal:  Antimicrob Agents Chemother       Date:  1996-02       Impact factor: 5.191

2.  Activity of lipid-soluble inhibitors of dihydrofolate reductase against Pneumocystis carinii in culture and in a rat model of infection.

Authors:  S F Queener; M S Bartlett; M A Jay; M M Durkin; J W Smith
Journal:  Antimicrob Agents Chemother       Date:  1987-09       Impact factor: 5.191

3.  Sterols of Pneumocystis carinii hominis organisms isolated from human lungs.

Authors:  E S Kaneshiro; Z Amit; J Chandra; R P Baughman; C Contini; B Lundgren
Journal:  Clin Diagn Lab Immunol       Date:  1999-11

4.  Quantification and assessment of viability of Pneumocystis carinii organisms by flow cytometry.

Authors:  S E Lapinsky; D Glencross; N G Car; J M Kallenbach; S Zwi
Journal:  J Clin Microbiol       Date:  1991-05       Impact factor: 5.948

5.  In vitro differentiation of human-derived Pneumocystis carinii.

Authors:  W Blumenfeld; J M Griffiss
Journal:  J Clin Microbiol       Date:  1989-03       Impact factor: 5.948

6.  Two clinical isolates of Candida glabrata exhibiting reduced sensitivity to amphotericin B both harbor mutations in ERG2.

Authors:  Claire M Hull; Oliver Bader; Josie E Parker; Michael Weig; Uwe Gross; Andrew G S Warrilow; Diane E Kelly; Steven L Kelly
Journal:  Antimicrob Agents Chemother       Date:  2012-10-01       Impact factor: 5.191

7.  Inhibitors of delta24(25) sterol methyltransferase block sterol synthesis and cell proliferation in Pneumocystis carinii.

Authors:  J A Urbina; G Visbal; L M Contreras; G McLaughlin; R Docampo
Journal:  Antimicrob Agents Chemother       Date:  1997-07       Impact factor: 5.191

8.  Close association of Pneumocystis carinii from infected rat lung with culture cells as shown by light and electron microscopy.

Authors:  M S Bartlett; M P Goheen; C H Lee; M M Shaw; M M Durkin; J W Smith
Journal:  Parasitol Res       Date:  1994       Impact factor: 2.289

9.  Susceptibility of Pneumocystis carinii to artemisinin in vitro.

Authors:  S Merali; S R Meshnick
Journal:  Antimicrob Agents Chemother       Date:  1991-06       Impact factor: 5.191

10.  Activity of topoisomerase inhibitors against Pneumocystis carinii in vitro and in an inoculated mouse model.

Authors:  J A Fishman; S F Queener; R S Roth; M S Bartlett
Journal:  Antimicrob Agents Chemother       Date:  1993-07       Impact factor: 5.191
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