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Literature DB >> 3871948

Stimulation of glycolysis and amino acid uptake in NRK-49F cells by transforming growth factor beta and epidermal growth factor.

Abstract

Glycolysis in normal resting rat kidney cells (NRK-49F) was stimulated by a 2-hr exposure to transforming growth factors prior to assay. Transforming growth factor beta (TGF-beta) was effective when added alone, and further addition of epidermal growth factor (EGF) had little effect. The stimulation by TGF-beta was abolished when cycloheximide was present during the incubation, suggesting that protein synthesis is required for the effect. Incubation of the cells with 25 mM methionine abolished the stimulation of glycolysis by TGF-beta. The uptake of methylaminoisobutyrate via system A was stimulated by either TGF-beta or EGF. The greater than 3-fold stimulation of uptake by 1 ng of pure TGF-beta per ml was usually somewhat enhanced on addition of 0.5 ng of EGF per ml. Moreover, an antiserum against EGF receptor partially depressed the response to TGF-beta, suggesting some overlapping interactions of EGF and TGF-beta.

Entities: Chemical Gene Species

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Year: 1985 PMID： 3871948 PMCID： PMC397258 DOI： 10.1073/pnas.82.5.1350

Source DB: PubMed Journal: Proc Natl Acad Sci U S A ISSN： 0027-8424 Impact factor: 11.205

13 in total

1. DISTINCT MEDIATING SYSTEMS FOR THE TRANSPORT OF NEUTRAL AMINO ACIDS BY THE EHRLICH CELL.

Authors: D L OXENDER; H N CHRISTENSEN
Journal: J Biol Chem Date: 1963-11 Impact factor: 5.157

2. Inhibition of alpha-aminoisobutyric acid transport in membrane vesicles from mouse fibroblasts after phosphorylation by cyclic AMP-dependent protein kinase.

Authors: M Nilsen-Hamilton; R T Hamilton
Journal: Biochim Biophys Acta Date: 1979-12-11

Review 3. Transport alterations in virus-transformed cells.

Authors: J R Parnes; K J Isselbacher
Journal: Prog Exp Tumor Res Date: 1978

4. Transport of amino acids by confluent and nonconfluent 3T3 and polyoma virus-transformed 3T3 cells growing on glass cover slips.

Authors: D O Foster; A B Pardee
Journal: J Biol Chem Date: 1969-05-25 Impact factor: 5.157

5. The role of ATPase in glycolysis of Ehrlich ascites tumor cells.

Authors: E Racker; J H Johnson; M T Blackwell
Journal: J Biol Chem Date: 1983-03-25 Impact factor: 5.157

6. Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes.

Authors: H Land; L F Parada; R A Weinberg
Journal: Nature Date: 1983 Aug 18-24 Impact factor: 49.962

7. Growth regulation and amino acid transport in epithelial cells: influence of culture conditions and transformation on A, ASC, and L transport activities.

Authors: P Boerner; M H Saier
Journal: J Cell Physiol Date: 1982-11 Impact factor: 6.384

8. Characteristics of antibodies to the epidermal growth factor receptor-kinase.

Authors: C M Stoscheck; G Carpenter
Journal: Arch Biochem Biophys Date: 1983-12 Impact factor: 4.013

9. Transforming growth factor-beta in human platelets. Identification of a major storage site, purification, and characterization.

Authors: R K Assoian; A Komoriya; C A Meyers; D M Miller; M B Sporn
Journal: J Biol Chem Date: 1983-06-10 Impact factor: 5.157

10. Cell density and amino acid transport in 3T3, SV3T3, and SV3T3 revertant cells.

Authors: A F Borghetti; G Piedimonte; M Tramacere; A Severini; P Ghiringhelli; G G Guidotti
Journal: J Cell Physiol Date: 1980-10 Impact factor: 6.384

21 in total

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Authors: T Kawamoto; M Nishi; K Takahashi; T Nishiyama; J D Sato; S Taniguchi
Journal: In Vitro Cell Dev Biol Date: 1989-10

2. Transforming growth factor type beta: rapid induction of fibrosis and angiogenesis in vivo and stimulation of collagen formation in vitro.

Authors: A B Roberts; M B Sporn; R K Assoian; J M Smith; N S Roche; L M Wakefield; U I Heine; L A Liotta; V Falanga; J H Kehrl
Journal: Proc Natl Acad Sci U S A Date: 1986-06 Impact factor: 11.205

3. Evolution of Escherichia coli during growth in a constant environment.

Authors: R B Helling; C N Vargas; J Adams
Journal: Genetics Date: 1987-07 Impact factor: 4.562

4. Hyperpolarized [1-¹³C]-Pyruvate Magnetic Resonance Spectroscopic Imaging of Prostate Cancer In Vivo Predicts Efficacy of Targeting the Warburg Effect.

Authors: Bradley T Scroggins; Masayuki Matsuo; Ayla O White; Keita Saito; Jeeva P Munasinghe; Carole Sourbier; Kazutoshi Yamamoto; Vivian Diaz; Yoichi Takakusagi; Kazuhiro Ichikawa; James B Mitchell; Murali C Krishna; Deborah E Citrin
Journal: Clin Cancer Res Date: 2018-03-29 Impact factor: 12.531

5. Five enzymes of the glycolytic pathway serve as substrates for purified epidermal-growth-factor-receptor kinase.

Authors: N Reiss; H Kanety; J Schlessinger
Journal: Biochem J Date: 1986-11-01 Impact factor: 3.857

6. Stimulation of glucose uptake by transforming growth factor beta: evidence for the requirement of epidermal growth factor-receptor activation.

Authors: W H Inman; S P Colowick
Journal: Proc Natl Acad Sci U S A Date: 1985-03 Impact factor: 11.205

7. Comparative and combined effects of transforming growth factors alpha and beta, interleukin-1 and interferon-gamma on rheumatoid synovial cell proliferation, glycolysis and prostaglandin E production.

Authors: D J Taylor; M Feldmann; J M Evanson; D E Woolley
Journal: Rheumatol Int Date: 1989 Impact factor: 2.631