Literature DB >> 3867007

Influence of alpha thalassaemia on haematological parameters in Polynesian patients.

K N Mickleson, M W Dixon, P J Hill, R Bluck, M Eales, J Rutherford, J Yakas, R J Trent.   

Abstract

DNA mapping of the alpha globin gene cluster in cord blood from Polynesians has shown an increased frequency of alpha thalassaemia and triplicated alpha genes. Reduced levels of haemoglobin, mean corpuscular haemoglobin or mean corpuscular volume in these neonates may indicate alpha thalassaemia. Recognition of this will avoid unnecessary haematological investigations and iron supplementation.

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Year:  1985        PMID: 3867007

Source DB:  PubMed          Journal:  N Z Med J        ISSN: 0028-8446


  3 in total

1.  Globin genes in Polynesians have many rearrangements including a recently described gamma gamma gamma gamma/.

Authors:  R J Trent; K N Mickleson; T Wilkinson; J Yakas; M W Dixon; P J Hill; H Kronenberg
Journal:  Am J Hum Genet       Date:  1986-09       Impact factor: 11.025

2.  Newborn splenic volumes vary under different malaria endemic conditions.

Authors:  J A Corkill; B J Brabin; D F MacGregor; M P Alpers; R D Milner
Journal:  Arch Dis Child       Date:  1989-04       Impact factor: 3.791

3.  Fetal Cytokine Balance, Erythropoietin and Thalassemia but Not Placental Malaria Contribute to Fetal Anemia Risk in Tanzania.

Authors:  Edward R Kabyemela; Michal Fried; Jonathan D Kurtis; Gwamaka Moses; J Patrick Gorres; Atis Muehlenbachs; Patrick E Duffy
Journal:  Front Immunol       Date:  2021-04-30       Impact factor: 7.561

  3 in total

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