Literature DB >> 3861331

Association of anthracycline derivatives with DNA: a fluorescence study.

L Valentini, V Nicolella, E Vannini, M Menozzi, S Penco, F Arcamone.   

Abstract

The DNA affinity for 26 anthracycline derivatives was studied by the quenching fluorescence technique. The stereochemical requirements for DNA intercalation are discussed. The relationship between the DNA affinity and bioactivity is also pointed out.

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Year:  1985        PMID： 3861331

Source DB:  PubMed          Journal:  Farmaco Sci        ISSN： 0430-0920


  11 in total

1.  Bis-intercalative dinuclear platinum(II) 6-phenyl-2,2'-bipyridine complexes exhibit enhanced DNA affinity but similar cytotoxicity compared to the mononuclear unit.

Authors:  Hing-Leung Chan; Dik-Lung Ma; Mengsu Yang; Chi-Ming Che
Journal:  J Biol Inorg Chem       Date:  2003-07-22       Impact factor: 3.358

2.  The development of new anticancer drugs.

Authors:  F M Arcamone
Journal:  World J Microbiol Biotechnol       Date:  1992-12       Impact factor: 3.312

3.  RNA nanoparticles harboring annexin A2 aptamer can target ovarian cancer for tumor-specific doxorubicin delivery.

Authors:  Fengmei Pi; Hui Zhang; Hui Li; Varatharasa Thiviyanathan; David G Gorenstein; Anil K Sood; Peixuan Guo
Journal:  Nanomedicine       Date:  2016-11-25       Impact factor: 5.307

4.  Fluorinated anthracyclines: interactions with DNA.

Authors:  K C Tonkin; R C Boston; R T Brownlee; D R Phillips
Journal:  Invest New Drugs       Date:  1990-11       Impact factor: 3.850

5.  Promoter-specific inhibition of transcription by daunorubicin in Saccharomyces cerevisiae.

Authors:  Silvia Marín; Sylvia Mansilla; Natàlia García-Reyero; Marta Rojas; José Portugal; Benjamin Piña
Journal:  Biochem J       Date:  2002-11-15       Impact factor: 3.857

6.  In vitro transcription analysis of the role of flanking sequence on the DNA sequence specificity of adriamycin.

Authors:  H Trist; D R Phillips
Journal:  Nucleic Acids Res       Date:  1989-05-25       Impact factor: 16.971

Review 7.  Anthracycline antitumour agents. A review of physicochemical, analytical and stability properties.

Authors:  J Bouma; J H Beijnen; A Bult; W J Underberg
Journal:  Pharm Weekbl Sci       Date:  1986-04-25

8.  DNA unwinding and inhibition of T4 DNA ligase by anthracyclines.

Authors:  A Montecucco; G Pedrali-Noy; S Spadari; E Zanolin; G Ciarrocchi
Journal:  Nucleic Acids Res       Date:  1988-05-11       Impact factor: 16.971

9.  Bis-daunomycin hydrazones: interactions with DNA.

Authors:  D R Phillips; R T Brownlee; J A Reiss; P A Scourides
Journal:  Invest New Drugs       Date:  1992-07       Impact factor: 3.850

10.  Beyond DNA binding - a review of the potential mechanisms mediating quinacrine's therapeutic activities in parasitic infections, inflammation, and cancers.

Authors:  Reza Ehsanian; Carter Van Waes; Stephan M Feller
Journal:  Cell Commun Signal       Date:  2011-05-15       Impact factor: 5.712
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