| Literature DB >> 385773 |
B Andersson, A C Skoglund, A Rosen.
Abstract
The function of mouse T lymphocytes with receptors for IgM-Fc was analyzed by using immunofluorescence and a column separation method. The cellular uptake of FITC-IgM was inhibited with unlabeled Fc5 mu. IgM-FcR+ cells were active in ADCC against IgM-sensitized target cells, but not against IgG-coated target cells. The cells mediating ADCC with IgM antibody were shown to be distinct and physically separable from those mediating ADCC with IgG antibody. Helper T lymphocytes for humoral antibody formation in a hapten-carrier system were shown to be IgM-FcR+ and Fc-IgG-.Entities:
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Year: 1979 PMID： 385773
Source DB: PubMed Journal: J Immunol ISSN： 0022-1767 Impact factor: 5.422