Literature DB >> 3856566

Inhibition of iron-molybdenum cofactor binding to component I of nitrogenase.

V K Shah, R A Ugalde, J Imperial, W J Brill.   

Abstract

Tetrathiomolybdate inhibits iron-molybdenum cofactor (FeMo cofactor) binding to component I of nitrogenase. Molybdenum-iron cluster (a subcomponent of FeMo cofactor) and tetrathiomolybdate inhibited FeMo cofactor activation of inactive nitrogenase component I in extracts of Azotobacter vinelandii and Klebsiella pneumoniae mutant strains defective in the biosynthesis of FeMo cofactor. Addition of tetrathiotungstate, the tungsten analog of tetrathiomolybdate, to the mutant extracts had no significant inhibitory effect on subsequent activation by FeMo cofactor.

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Year:  1985        PMID： 3856566

Source DB:  PubMed          Journal:  J Biol Chem        ISSN： 0021-9258            Impact factor:   5.157


  8 in total

1.  ApoNifH functions in iron-molybdenum cofactor synthesis and apodinitrogenase maturation.

Authors:  P Rangaraj; V K Shah; P W Ludden
Journal:  Proc Natl Acad Sci U S A       Date:  1997-10-14       Impact factor: 11.205

2.  Identification of a nitrogenase FeMo cofactor precursor on NifEN complex.

Authors:  Yilin Hu; Aaron W Fay; Markus W Ribbe
Journal:  Proc Natl Acad Sci U S A       Date:  2005-02-22       Impact factor: 11.205

3.  NifB-dependent in vitro synthesis of the iron-molybdenum cofactor of nitrogenase.

Authors:  Leonardo Curatti; Paul W Ludden; Luis M Rubio
Journal:  Proc Natl Acad Sci U S A       Date:  2006-03-27       Impact factor: 11.205

4.  Nucleotide and divalent cation specificity of in vitro iron-molybdenum cofactor synthesis.

Authors:  R Chatterjee; R M Allen; V K Shah; P W Ludden
Journal:  J Bacteriol       Date:  1994-05       Impact factor: 3.490

5.  Synthesis of the iron-molybdenum cofactor of nitrogenase is inhibited by a low-molecular-weight metabolite of Klebsiella pneumoniae.

Authors:  D M Downs; P W Ludden; V K Shah
Journal:  J Bacteriol       Date:  1990-10       Impact factor: 3.490

6.  In vitro synthesis of the iron-molybdenum cofactor of nitrogenase.

Authors:  V K Shah; J Imperial; R A Ugalde; P W Ludden; W J Brill
Journal:  Proc Natl Acad Sci U S A       Date:  1986-03       Impact factor: 11.205

7.  The chaperone GroEL is required for the final assembly of the molybdenum-iron protein of nitrogenase.

Authors:  M W Ribbe; B K Burgess
Journal:  Proc Natl Acad Sci U S A       Date:  2001-05-01       Impact factor: 11.205

8.  In vitro synthesis of the iron-molybdenum cofactor of nitrogenase from iron, sulfur, molybdenum, and homocitrate using purified proteins.

Authors:  Leonardo Curatti; Jose A Hernandez; Robert Y Igarashi; Basem Soboh; Dehua Zhao; Luis M Rubio
Journal:  Proc Natl Acad Sci U S A       Date:  2007-10-31       Impact factor: 11.205
  8 in total

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