Literature DB >> 3856475

Localization of anti-osteogenic sarcoma monoclonal antibody 791T/36 in a primary human osteogenic sarcoma and its subsequent xenograft in immunodeprived mice.

M V Pimm, A C Perkins, N C Armitage, R W Baldwin.   

Abstract

A primary human osteogenic sarcoma was visualized in situ by external gamma-camera imaging following administration of 131I-labelled anti-osteogenic sarcoma monoclonal antibody 791T/36. A xenograft of the tumour established in immunodeprived mice also showed localization of 131I-791T/36 determined by both gamma-camera imaging and organ distribution studies. Radiolabelled normal immunoglobulin showed no tumour localization. Expression of the 791T/36-defined antigen on xenografted tissue was further confirmed by reaction of its in vitro-cultured cells with fluorescein-labelled 791T/36 antibody.

Entities:  

Mesh：

Substances：

Year:  1985        PMID： 3856475     DOI： 10.1007/bf00199306

Source DB:  PubMed          Journal:  Cancer Immunol Immunother        ISSN： 0340-7004            Impact factor:   6.968


  22 in total

1.  In vivo localization of anti-osteogenic sarcoma 791T monoclonal antibody in osteogenic sarcoma xenografts.

Authors:  M V Pimm; M J Embleton; A C Perkins; M R Price; R A Robins; G R Robinson; R W Baldwin
Journal:  Int J Cancer       Date:  1982-07-15       Impact factor: 7.396

2.  Experimental studies of tumor radioimmunodetection using antibody mixtures against carcinoembryonic antigen (CEA) and colon-specific antigen-p (CSAp).

Authors:  S A Gaffar; K D Pant; D Shochat; S J Bennett; D M Goldenberg
Journal:  Int J Cancer       Date:  1981-01-15       Impact factor: 7.396

3.  Interferon-alpha conjugation to human osteogenic sarcoma monoclonal antibody 791T/36.

Authors:  J M Pelham; J D Gray; G R Flannery; M V Pimm; R W Baldwin
Journal:  Cancer Immunol Immunother       Date:  1983       Impact factor: 6.968

4.  Tumor localization of CEA-containing human tumors in nude mice by means of monoclonal anti-CEA antibodies.

Authors:  A Hedin; B Wahren; S Hammarström
Journal:  Int J Cancer       Date:  1982-11-15       Impact factor: 7.396

5.  Immunomodulation: NK cells activated by interferon-conjugated monoclonal antibody against human osteosarcoma.

Authors:  G R Flannery; J M Pelham; J D Gray; R W Baldwin
Journal:  Eur J Cancer Clin Oncol       Date:  1984-06

6.  Radioimmunodetection of human tumor xenografts by monoclonal antibodies.

Authors:  D Herlyn; J Powe; A Alavi; J A Mattis; M Herlyn; C Ernst; R Vaum; H Koprowski
Journal:  Cancer Res       Date:  1983-06       Impact factor: 12.701

7.  Characteristics of a cell surface antigen defined by an anti-human osteogenic sarcoma monoclonal antibody.

Authors:  M R Price; D G Campbell; R A Robins; R W Baldwin
Journal:  Eur J Cancer Clin Oncol       Date:  1983-01

8.  Localisation of human osteosarcoma by antitumour monoclonal antibody.

Authors:  P A Farrands; A Perkins; L Sully; J S Hopkins; M V Pimm; R W Baldwin; J D Hardcastle
Journal:  J Bone Joint Surg Br       Date:  1983-11

9.  Antitumour reactions of monoclonal antibody against a human osteogenic-sarcoma cell line.

Authors:  M J Embleton; B Gunn; V S Byers; R W Baldwin
Journal:  Br J Cancer       Date:  1981-05       Impact factor: 7.640

10.  Localization of human tumour xenografts after i.v. administration of radiolabeled monoclonal antibodies.

Authors:  V Moshakis; R A McIlhinney; D Raghavan; A M Neville
Journal:  Br J Cancer       Date:  1981-07       Impact factor: 7.640
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.