| Literature DB >> 385030 |
P J Selby, E Heyderman, J Gibbs, M J Peckham.
Abstract
Serial transplantation of an HCG-producing human testicular teratoma in immune-deprived mice is described. The xenografted tumour was compared to the tumour of origin in histology, immunohistochemistry (using an immune peroxidase technique to localize HCG) autoradiography, marker production and growth rate. It is concluded that the xenograft retained the characteristics of the original tumour with the exception of a reduction in HCG-producing elements at transplantation beyond 5 serial passages.Entities:
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Year: 1979 PMID: 385030 PMCID: PMC2009907 DOI: 10.1038/bjc.1979.104
Source DB: PubMed Journal: Br J Cancer ISSN: 0007-0920 Impact factor: 7.640