Literature DB >> 385030

A human testicular teratoma serially transplanted in immune-deprived mice.

P J Selby, E Heyderman, J Gibbs, M J Peckham.   

Abstract

Serial transplantation of an HCG-producing human testicular teratoma in immune-deprived mice is described. The xenografted tumour was compared to the tumour of origin in histology, immunohistochemistry (using an immune peroxidase technique to localize HCG) autoradiography, marker production and growth rate. It is concluded that the xenograft retained the characteristics of the original tumour with the exception of a reduction in HCG-producing elements at transplantation beyond 5 serial passages.

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Year:  1979        PMID: 385030      PMCID: PMC2009907          DOI: 10.1038/bjc.1979.104

Source DB:  PubMed          Journal:  Br J Cancer        ISSN: 0007-0920            Impact factor:   7.640


  10 in total

1.  The biology of testicular cancer. III. Heterotransplanted choriocarcinomas.

Authors:  E L VERNEY; G B PIERCE; F J DIXON
Journal:  Cancer Res       Date:  1959-07       Impact factor: 12.701

2.  Peroxidase-labeled antibody. A new method of conjugation.

Authors:  P K Nakane; A Kawaoi
Journal:  J Histochem Cytochem       Date:  1974-12       Impact factor: 2.479

3.  A radioimmunoassay which specifically measures human chorionic gonadotropin in the presence of human luteinizing hormone.

Authors:  J L Vaitukaitis; G D Braunstein; G T Ross
Journal:  Am J Obstet Gynecol       Date:  1972-07-15       Impact factor: 8.661

4.  Enhanced post-irradiation recovery of the haemopoietic system in animals pretreated with a variety of cytotoxic agents.

Authors:  J L Millar; N M Blackett; B N Hudspith
Journal:  Cell Tissue Kinet       Date:  1978-09

5.  Letter: Syncytiotrophoblasts in malignant testicular tumours.

Authors:  E Heyderman; A M Neville
Journal:  Lancet       Date:  1976-07-10       Impact factor: 79.321

6.  Growth kinetics of human large bowel cancer growing in immune-deprived mice and some chemotherapeutic observations.

Authors:  L F Lamerton; G G Steel
Journal:  Cancer       Date:  1975-12       Impact factor: 6.860

7.  Heterotransplantation of human malignant tumors in "nude" thymusless mice. II. Malignant tumors induced by injection of cell cultures derived from human solid tumors.

Authors:  B C Giovanella; J S Stehlin; L J Williams
Journal:  J Natl Cancer Inst       Date:  1974-03       Impact factor: 13.506

8.  The growth of human tumours in immunosuppressed mice and their response to chemotherapy.

Authors:  M C Berenbaum; C E Sheard; J R Reittie; R V Bundick
Journal:  Br J Cancer       Date:  1974-07       Impact factor: 7.640

9.  Improved immune-suppression techniques for the exongrafting of human tumours.

Authors:  G G Steel; V D Courtenay; A Y Rostom
Journal:  Br J Cancer       Date:  1978-02       Impact factor: 7.640

10.  Maintenance of biological and biochemical characteristics of human colorectal tumours during serial passage in immune-deprived mice.

Authors:  J A Houghton; D M Taylor
Journal:  Br J Cancer       Date:  1978-02       Impact factor: 7.640

  10 in total
  7 in total

1.  Expanding the concept of patient-derived xenografts cohorts in head and neck cancer: current and future perspectives.

Authors:  Zhi Yuan Zhang; Shu Yang Sun
Journal:  Hua Xi Kou Qiang Yi Xue Za Zhi       Date:  2021-12-01

2.  Advantages in combination chemotherapy using cisplatin and its analogues for human testicular tumor xenografts.

Authors:  S Hida; K Okada; O Yoshida
Journal:  Jpn J Cancer Res       Date:  1990-04

3.  Ovarian tumour xenografts in the study of the biology of human epithelial ovarian cancer.

Authors:  M L Friedlander; P Russell; I W Taylor; M H Tattersall
Journal:  Br J Cancer       Date:  1985-03       Impact factor: 7.640

4.  Limitations of the human tumour xenograft system in individual patient drug sensitivity testing.

Authors:  M J Bailey; A J Jones; A J Shorthouse; D Raghaven; P Selby; J Gibbs; M J Peckham
Journal:  Br J Cancer       Date:  1984-11       Impact factor: 7.640

5.  A human choriocarcinoma xenograft in nude mice; a model for the study of antibody localization.

Authors:  F Searle; J Boden; J C Lewis; K D Bagshawe
Journal:  Br J Cancer       Date:  1981-08       Impact factor: 7.640

6.  Human tumour xenografts established and serially transplanted in mice immunologically deprived by thymectomy, cytosine arabinoside and whole-body irradiation.

Authors:  P J Selby; J M Thomas; P Monaghan; J Sloane; M J Peckham
Journal:  Br J Cancer       Date:  1980-01       Impact factor: 7.640

7.  Comparison of Magnetic Resonance Imaging and Serum Biomarkers for Detection of Human Pluripotent Stem Cell-Derived Teratomas.

Authors:  Johannes Riegler; Antje Ebert; Xulei Qin; Qi Shen; Mouer Wang; Mohamed Ameen; Kazuki Kodo; Sang-Ging Ong; Won Hee Lee; Grace Lee; Evgenios Neofytou; Joseph D Gold; Andrew J Connolly; Joseph C Wu
Journal:  Stem Cell Reports       Date:  2016-01-14       Impact factor: 7.765

  7 in total

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