Literature DB >> 3840790

Luminamicin, a new antibiotic. Production, isolation and physico-chemical and biological properties.

S Omura, R Iwata, Y Iwai, S Taga, Y Tanaka, H Tomoda.   

Abstract

A new antibiotic, luminamicin, was isolated from the culture broth of an actinomycete strain OMR-59. It exhibits antibacterial activity against anaerobic bacteria, especially against Clostridium sp. The molecular formula of the antibiotic was determined as C32H38O12 on the basis of high resolution mass spectrum, elemental analysis and NMR spectrum.

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Year:  1985        PMID： 3840790     DOI： 10.7164/antibiotics.38.1322

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN： 0021-8820            Impact factor:   2.649


  4 in total

1.  Stereostructure of luminamicin, an anaerobic antibiotic, via molecular dynamics, NMR spectroscopy, and the modified Mosher method.

Authors:  Hiroaki Gouda; Toshiaki Sunazuka; Hideaki Ui; Masaki Handa; Yusuke Sakoh; Yuzuru Iwai; Shuichi Hirono; Satoshi Omura
Journal:  Proc Natl Acad Sci U S A       Date:  2005-12-12       Impact factor: 11.205

Review 2.  Philosophy of new drug discovery.

Authors:  S Omura
Journal:  Microbiol Rev       Date:  1986-09

3.  Toward the total synthesis of luminamicin; an anaerobic antibiotic: construction of highly functionalized cis-decalin containing a bridged ether moiety.

Authors:  Hiroyasu Ando; Aoi Kimishima; Motoyoshi Ohara; Tomoyasu Hirose; Takanori Matsumaru; Hirokazu Takada; Keisuke Morodome; Takehiro Miyamoto; Akihiro Sugawara; Satoshi Ōmura; Toshiaki Sunazuka
Journal:  J Antibiot (Tokyo)       Date:  2017-07-05       Impact factor: 2.649

4.  A [6+4]-cycloaddition adduct is the biosynthetic intermediate in streptoseomycin biosynthesis.

Authors:  Kai Biao Wang; Wen Wang; Bo Zhang; Xin Wang; Yu Chen; Hong Jie Zhu; Yong Liang; Ren Xiang Tan; Hui Ming Ge
Journal:  Nat Commun       Date:  2021-04-07       Impact factor: 14.919
  4 in total

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