Literature DB >> 383108

A controlled study of the analgetic effect of two non-steroidal anti-inflammatory drugs in cancer pain.

G Martino, A Emanueli, V Mandelli, V Ventafridda.   

Abstract

With a subjective response technique the analgetic activity of two non-steroidal anti-inflammatory agents which greatly differ in kinetics is compared. The double-blind cross-over trial was carried out in 18 patients of both sexes suffering from pain due to malignant tumours who received single doses of 200 mg indoprofen and 250 mg naproxen p.o. Both compounds were efficacious and there was no difference in the duration of their activity in spite of the great difference between their half-lives.

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Year:  1978        PMID: 383108

Source DB:  PubMed          Journal:  Arzneimittelforschung        ISSN: 0004-4172


  3 in total

Review 1.  Non-steroidal anti-inflammatory analgesics other than salicylates.

Authors:  R N Brogden
Journal:  Drugs       Date:  1986       Impact factor: 9.546

Review 2.  Use of non-steroidal anti-inflammatory drugs in the treatment of pain in cancer.

Authors:  V Ventafridda; C Fochi; D De Conno; E Sganzerla
Journal:  Br J Clin Pharmacol       Date:  1980-10       Impact factor: 4.335

Review 3.  Naproxen up to date: a review of its pharmacological properties and therapeutic efficacy and use in rheumatic diseases and pain states.

Authors:  R N Brogden; R C Heel; T M Speight; G S Avery
Journal:  Drugs       Date:  1979-10       Impact factor: 9.546

  3 in total

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