Literature DB >> 38218

Separation of opioid peptides utilizing high performance liquid chromatography.

R V Lewis, S Stein, S Udenfriend.   

Abstract

Chromatographic procedures have been developed for resolving all of the known enkephalins and endorphins on a single column. The effect of eluant pH on the retention times and separation of the enkephalins and beta-endorphin was determined. By combining these separations with a sensitive radioreceptor assay it is possible to assay all of the opioid peptides in the pituitary gland or in various regions of the brain from individual small laboratory animals.

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Year:  1979        PMID: 38218     DOI: 10.1111/j.1399-3011.1979.tb01911.x

Source DB:  PubMed          Journal:  Int J Pept Protein Res        ISSN: 0367-8377


  4 in total

1.  Determination of beta-endorphin and substance P in small volumes of human cerebrospinal fluid.

Authors:  K Henning; T M Wallasch; H Przuntek
Journal:  J Neural Transm       Date:  1986       Impact factor: 3.575

2.  Probable precursors of [Leu]enkephalin and [Met]enkephalin in adrenal medulla: peptides of 3-5 kilodaltons.

Authors:  S Kimura; R V Lewis; A S Stern; J Rossier; S Stein; S Udenfriend
Journal:  Proc Natl Acad Sci U S A       Date:  1980-03       Impact factor: 11.205

3.  Opioid polypeptides in guinea pig pancreas.

Authors:  A S Stern; R J Wurzburger; R Barkey; S Spector
Journal:  Proc Natl Acad Sci U S A       Date:  1982-11       Impact factor: 11.205

4.  Enzymatic reduction of protein-bound methionine sulfoxide.

Authors:  N Brot; L Weissbach; J Werth; H Weissbach
Journal:  Proc Natl Acad Sci U S A       Date:  1981-04       Impact factor: 11.205

  4 in total

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