Literature DB >> 3820267

Opsonic monoclonal antibodies against lipopolysaccharide antigens of Leptospira interrogans serovar hardjo.

H E Farrelly, B Adler, S Faine.   

Abstract

Six monoclonal antibodies produced from mice immunised with Leptospira interrogans serovar hardjo were directed against determinants in the leptospiral lipopolysaccharide, as indicated by immunodiffusion and enzyme immunoassay (EIA), and opsonised leptospires for phagocytosis by mouse macrophages. Their specificities were studied by agglutination and EIA. Five antibodies reacted with some, but not all, members of the Sejroe and Hebdomadis serogroups, and one antibody agglutinated exclusively members of the Sejroe group thus indentifying a serogroup-specific epitope. None of the six antibodies reacted with representative serovars of any other serogroup.

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Year:  1987        PMID: 3820267     DOI: 10.1099/00222615-23-1-1

Source DB:  PubMed          Journal:  J Med Microbiol        ISSN: 0022-2615            Impact factor:   2.472


  16 in total

1.  Functional analysis of genes in the rfb locus of Leptospira borgpetersenii serovar Hardjo subtype Hardjobovis.

Authors:  D M Bulach; T Kalambaheti; A de la Peña-Moctezuma; B Adler
Journal:  Infect Immun       Date:  2000-07       Impact factor: 3.441

2.  Development of a monoclonal antibody-based competitive enzyme-linked immunosorbent assay for the detection of Leptospira borgpetersenii serovar hardjo type hardjobovis antibodies in bovine sera.

Authors:  O Surujballi; D Henning; R Marenger; C Howlett
Journal:  Can J Vet Res       Date:  1997-10       Impact factor: 1.310

3.  Surfaceome of Leptospira spp.

Authors:  Paul A Cullen; Xiaoyi Xu; James Matsunaga; Yolanda Sanchez; Albert I Ko; David A Haake; Ben Adler
Journal:  Infect Immun       Date:  2005-08       Impact factor: 3.441

4.  Use of recombinant flagellin protein as a tracer antigen in a fluorescence polarization assay for diagnosis of leptospirosis.

Authors:  N I Bughio; M Lin; O P Surujballi
Journal:  Clin Diagn Lab Immunol       Date:  1999-07

5.  Characterization of an antigenic oligosaccharide from Leptospira interrogans serovar pomona and its role in immunity.

Authors:  A Midwinter; T Vinh; S Faine; B Adler
Journal:  Infect Immun       Date:  1994-12       Impact factor: 3.441

6.  LipL21 is a novel surface-exposed lipoprotein of pathogenic Leptospira species.

Authors:  Paul A Cullen; David A Haake; Dieter M Bulach; Richard L Zuerner; Ben Adler
Journal:  Infect Immun       Date:  2003-05       Impact factor: 3.441

Review 7.  The leptospiral outer membrane.

Authors:  David A Haake; Wolfram R Zückert
Journal:  Curr Top Microbiol Immunol       Date:  2015       Impact factor: 4.291

8.  Global analysis of outer membrane proteins from Leptospira interrogans serovar Lai.

Authors:  Paul A Cullen; Stuart J Cordwell; Dieter M Bulach; David A Haake; Ben Adler
Journal:  Infect Immun       Date:  2002-05       Impact factor: 3.441

Review 9.  Outer membrane proteins of pathogenic spirochetes.

Authors:  Paul A Cullen; David A Haake; Ben Adler
Journal:  FEMS Microbiol Rev       Date:  2004-06       Impact factor: 16.408

10.  Antigens recognized by the human immune response to severe leptospirosis in Barbados.

Authors:  A J Chapman; C O Everard; S Faine; B Adler
Journal:  Epidemiol Infect       Date:  1991-08       Impact factor: 2.451

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