Literature DB >> 3814771

Inhibition and reversal of denervation-induced atrophy by the beta-agonist growth promoter, clenbuterol.

C A Maltin, P J Reeds, M I Delday, S M Hay, F G Smith, G E Lobley.   

Abstract

Dietary administration of the growth promoter, clenbuterol, ameliorated denervation-induced atrophy in rat soleus muscles. In acutely denervated muscles the drug inhibited the appearance of atrophy, and in chronically denervated muscles the atrophy was almost fully reversed. Responses in slow twitch oxidative fibres were particularly marked.

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Year:  1986        PMID： 3814771     DOI： 10.1007/bf01117104

Source DB:  PubMed          Journal:  Biosci Rep        ISSN： 0144-8463            Impact factor:   3.840


  7 in total

1.  The effects of clenbuterol on satellite cell activation and the regeneration of skeletal muscle: an autoradiographic and morphometric study of whole muscle transplants in mice.

Authors:  P Roberts; J K McGeachie
Journal:  J Anat       Date:  1992-02       Impact factor: 2.610

Review 2.  Regulation of protein turnover in skeletal and cardiac muscle.

Authors:  P H Sugden; S J Fuller
Journal:  Biochem J       Date:  1991-01-01       Impact factor: 3.857

3.  Evidence that the hypertrophic action of clenbuterol on denervated rat muscle is not propranolol-sensitive.

Authors:  C A Maltin; S M Hay; M I Delday; P J Reeds; R M Palmer
Journal:  Br J Pharmacol       Date:  1989-04       Impact factor: 8.739

4.  The action of the beta-agonist clenbuterol on protein metabolism in innervated and denervated phasic muscles.

Authors:  C A Maltin; S M Hay; M I Delday; G E Lobley; P J Reeds
Journal:  Biochem J       Date:  1989-08-01       Impact factor: 3.857

5.  Muscle protein waste in tumor-bearing rats is effectively antagonized by a beta 2-adrenergic agonist (clenbuterol). Role of the ATP-ubiquitin-dependent proteolytic pathway.

Authors:  P Costelli; C García-Martínez; M Llovera; N Carbó; F J López-Soriano; N Agell; L Tessitore; F M Baccino; J M Argilés
Journal:  J Clin Invest       Date:  1995-05       Impact factor: 14.808

6.  Propranolol retards revascularisation and impedes early myogenesis in regenerating skeletal muscle transplants: an autoradiographic and morphometric study in mice.

Authors:  P Roberts; J K McGeachie
Journal:  J Anat       Date:  1992-08       Impact factor: 2.610

7.  Using AAV vectors expressing the β2-adrenoceptor or associated Gα proteins to modulate skeletal muscle mass and muscle fibre size.

Authors:  Adam Hagg; Timothy D Colgan; Rachel E Thomson; Hongwei Qian; Gordon S Lynch; Paul Gregorevic
Journal:  Sci Rep       Date:  2016-03-14       Impact factor: 4.379
  7 in total

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