Literature DB >> 3800960

Fat synthesis in adipose tissue. An examination of stoichiometric constraints.

D A Fell, J R Small.   

Abstract

The requirement for net balance of synthesis, degradation and transport for all intermediates in the pathways from glucose to fat imposes constraints on the balance of fluxes between different pathways. Linear programming has been used to examine the interactions between these constraints on metabolism in adipocytes and the requirement for efficiency in the conversion of glucose into fat. The circumstances under which excessive ATP synthesis would accompany this conversion have been investigated.

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Year:  1986        PMID： 3800960      PMCID： PMC1147204          DOI： 10.1042/bj2380781

Source DB:  PubMed          Journal:  Biochem J        ISSN： 0264-6021            Impact factor:   3.857


  11 in total

1.  Evidence that fatty acid synthesis in the interscapular brown adipose tissue of cold-adapted rats is increased in vivo by insulin by mechanisms involving parallel activation of pyruvate dehydrogenase and acetyl-coenzyme A carboxylase.

Authors:  J G McCormack; R M Denton
Journal:  Biochem J       Date:  1977-09-15       Impact factor: 3.857

2.  Conversion of carbohydrate to fat in adipose tissue: an energy-yielding and, therefore, self-limiting process.

Authors:  J P Flatt
Journal:  J Lipid Res       Date:  1970-03       Impact factor: 5.922

3.  Hamster brown-adipose-tissue mitochondria. The control of respiration and the proton electrochemical potential gradient by possible physiological effectors of the proton conductance of the inner membrane.

Authors:  D G Nicholls
Journal:  Eur J Biochem       Date:  1974-12-02

4.  The metabolism of tritiated glucose by rat adipose tissue.

Authors:  J Katz; R Rognstad
Journal:  J Biol Chem       Date:  1966-08-10       Impact factor: 5.157

5.  The optimal efficiency and the economic degrees of coupling of oxidative phosphorylation.

Authors:  J W Stucki
Journal:  Eur J Biochem       Date:  1980-08

6.  Fatty acid synthesis in vivo in brown adipose tissue, liver and white adipose tissue of the cold-acclimated rat.

Authors:  P Trayhurn
Journal:  FEBS Lett       Date:  1979-08-01       Impact factor: 4.124

7.  The intracellular localization of enzymes in white-adipose-tissue fat-cells and permeability properties of fat-cell mitochondria. Transfer of acetyl units and reducing power between mitochondria and cytoplasm.

Authors:  B R Martin; R M Denton
Journal:  Biochem J       Date:  1970-05       Impact factor: 3.857

Review 8.  Secretion of mammalian polypeptides from yeast.

Authors:  B L Carter; S Doel; A R Goodey; J R Piggott; M E Watson
Journal:  Microbiol Sci       Date:  1986-01

9.  Quantitative analysis of intermediary metabolism in hepatocytes incubated in the presence and absence of glucagon with a substrate mixture containing glucose, ribose, fructose, alanine and acetate.

Authors:  M Rabkin; J J Blum
Journal:  Biochem J       Date:  1985-02-01       Impact factor: 3.857

10.  The game of the pentose phosphate cycle.

Authors:  E Meléndez-Hevia; A Isidoro
Journal:  J Theor Biol       Date:  1985-11-21       Impact factor: 2.691
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  71 in total

1.  Activity and metabolic roles of the pentose phosphate cycle in several rat tissues.

Authors:  H Cabezas; R R Raposo; E Meléndez-Hevia
Journal:  Mol Cell Biochem       Date:  1999-11       Impact factor: 3.396

2.  Regulatory on/off minimization of metabolic flux changes after genetic perturbations.

Authors:  Tomer Shlomi; Omer Berkman; Eytan Ruppin
Journal:  Proc Natl Acad Sci U S A       Date:  2005-05-16       Impact factor: 11.205

3.  Quantitative flux coupling analysis.

Authors:  Mojtaba Tefagh; Stephen P Boyd
Journal:  J Math Biol       Date:  2018-12-10       Impact factor: 2.259

4.  Use of game-theoretical methods in biochemistry and biophysics.

Authors:  Stefan Schuster; Jan-Ulrich Kreft; Anja Schroeter; Thomas Pfeiffer
Journal:  J Biol Phys       Date:  2008-08-06       Impact factor: 1.365

5.  Network organization of cell metabolism: monosaccharide interconversion.

Authors:  J C Nuño; I Sánchez-Valdenebro; C Pérez-Iratxeta; E Meléndez-Hevia; F Montero
Journal:  Biochem J       Date:  1997-05-15       Impact factor: 3.857

6.  On the topological features of optimal metabolic pathway regimes.

Authors:  S M See; J P Dean; G Dervakos
Journal:  Appl Biochem Biotechnol       Date:  1996-09       Impact factor: 2.926

7.  Flux balance analysis of barley seeds: a computational approach to study systemic properties of central metabolism.

Authors:  Eva Grafahrend-Belau; Falk Schreiber; Dirk Koschützki; Björn H Junker
Journal:  Plant Physiol       Date:  2008-11-05       Impact factor: 8.340

8.  Supply-Side Analysis of Growth of Bacillus subtilis on Glucose-Citrate Medium: Feasible Network Alternatives and Yield Optimality.

Authors:  J Lee; A Goel; M M Ataai; M M Domach
Journal:  Appl Environ Microbiol       Date:  1997-02       Impact factor: 4.792

9.  Integrating quantitative proteomics and metabolomics with a genome-scale metabolic network model.

Authors:  Keren Yizhak; Tomer Benyamini; Wolfram Liebermeister; Eytan Ruppin; Tomer Shlomi
Journal:  Bioinformatics       Date:  2010-06-15       Impact factor: 6.937

10.  In silico approaches to study mass and energy flows in microbial consortia: a syntrophic case study.

Authors:  Reed Taffs; John E Aston; Kristen Brileya; Zackary Jay; Christian G Klatt; Shawn McGlynn; Natasha Mallette; Scott Montross; Robin Gerlach; William P Inskeep; David M Ward; Ross P Carlson
Journal:  BMC Syst Biol       Date:  2009-12-10
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