Literature DB >> 3800883

Effects of low-protein diet and starvation on the activity of branched-chain 2-oxo acid dehydrogenase kinase in rat liver and heart.

J Espinal, M Beggs, H Patel, P J Randle.   

Abstract

The activity of branched-chain 2-oxo acid dehydrogenase kinase was 3-fold greater in extracts of heart mitochondria than in extracts of liver mitochondria from rats fed on normal diet. Feeding rats on a 0%-casein diet for 10 days increased the activity of branched-chain kinase 4-fold in extracts of liver mitochondria and in branched-chain dehydrogenase complex purified from such extracts; starvation (48 h) was without effect. In extract of heart mitochondria, kinase activity was increased 2-fold by feeding on 0%-casein diet and 1.5-fold by 48 h of starvation.

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Year:  1986        PMID: 3800883      PMCID: PMC1146979          DOI: 10.1042/bj2370285

Source DB:  PubMed          Journal:  Biochem J        ISSN: 0264-6021            Impact factor:   3.857


  12 in total

1.  Assay of cyclic AMP-dependent protein kinases.

Authors:  J D Corbin; E M Reimann
Journal:  Methods Enzymol       Date:  1974       Impact factor: 1.600

2.  Cleavage of structural proteins during the assembly of the head of bacteriophage T4.

Authors:  U K Laemmli
Journal:  Nature       Date:  1970-08-15       Impact factor: 49.962

3.  Evidence that the mitochondrial activator of phosphorylated branched-chain 2-oxoacid dehydrogenase complex is the dissociated E1 component of the complex.

Authors:  S J Yeaman; K G Cook; R W Boyd; R Lawson
Journal:  FEBS Lett       Date:  1984-06-25       Impact factor: 4.124

4.  Activity state of the branched chain alpha-ketoacid dehydrogenase complex in heart, liver, and kidney of normal, fasted, diabetic, and protein-starved rats.

Authors:  S E Gillim; R Paxton; G A Cook; R A Harris
Journal:  Biochem Biophys Res Commun       Date:  1983-02-28       Impact factor: 3.575

5.  Inactivation of rat liver and kidney branched chain 2-oxoacid dehydrogenase complex by adenosine triphosphate.

Authors:  K S Lau; H R Fatania; P J Randle
Journal:  FEBS Lett       Date:  1981-04-06       Impact factor: 4.124

6.  Activation of phosphorylated branched chain 2-oxoacid dehydrogenase complex.

Authors:  H R Fatania; K S Lau; P J Randle
Journal:  FEBS Lett       Date:  1982-10-04       Impact factor: 4.124

7.  Regulation of kinase reactions in pig heart pyruvate dehydrogenase complex.

Authors:  A L Kerbey; P M Radcliffe; P J Randle; P H Sugden
Journal:  Biochem J       Date:  1979-08-01       Impact factor: 3.857

8.  Regulation of heart muscle pyruvate dehydrogenase kinase.

Authors:  R H Cooper; P J Randle; R M Denton
Journal:  Biochem J       Date:  1974-12       Impact factor: 3.857

9.  Rat tissue concentrations of branched-chain 2-oxo acid dehydrogenase complex. Re-evaluation by immunoassay and bioassay.

Authors:  P A Patston; J Espinal; J M Shaw; P J Randle
Journal:  Biochem J       Date:  1986-04-15       Impact factor: 3.857

10.  Effects of diet and of alloxan-diabetes on the activity of branched-chain 2-oxo acid dehydrogenase complex and of activator protein in rat tissues.

Authors:  P A Patston; J Espinal; P J Randle
Journal:  Biochem J       Date:  1984-09-15       Impact factor: 3.857

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  10 in total

Review 1.  The 2-oxo acid dehydrogenase complexes: recent advances.

Authors:  S J Yeaman
Journal:  Biochem J       Date:  1989-02-01       Impact factor: 3.857

2.  Evidence that rat liver pyruvate dehydrogenase kinase activator protein is a pyruvate dehydrogenase kinase.

Authors:  S C Mistry; D A Priestman; A L Kerbey; P J Randle
Journal:  Biochem J       Date:  1991-05-01       Impact factor: 3.857

3.  Branched-chain 6-ketoacid dehydrogenase kinase: A mammalian enzyme with histidine kinase activity.

Authors:  Michael V Lasker; Philip Thai; Paul G Besant; Cuong D Bui; Srinivas Naidu; Christoph W Turck
Journal:  J Biomol Tech       Date:  2002-12

Review 4.  Assessing Cardiac Metabolism: A Scientific Statement From the American Heart Association.

Authors:  Heinrich Taegtmeyer; Martin E Young; Gary D Lopaschuk; E Dale Abel; Henri Brunengraber; Victor Darley-Usmar; Christine Des Rosiers; Robert Gerszten; Jan F Glatz; Julian L Griffin; Robert J Gropler; Hermann-Georg Holzhuetter; Jorge R Kizer; E Douglas Lewandowski; Craig R Malloy; Stefan Neubauer; Linda R Peterson; Michael A Portman; Fabio A Recchia; Jennifer E Van Eyk; Thomas J Wang
Journal:  Circ Res       Date:  2016-03-24       Impact factor: 17.367

5.  Effects of clofibric acid on the activity and activity state of the hepatic branched-chain 2-oxo acid dehydrogenase complex.

Authors:  Y Zhao; J Jaskiewicz; R A Harris
Journal:  Biochem J       Date:  1992-07-01       Impact factor: 3.857

6.  Obesity-related elevations in plasma leucine are associated with alterations in enzymes involved in branched-chain amino acid metabolism.

Authors:  Pengxiang She; Cynthia Van Horn; Tanya Reid; Susan M Hutson; Robert N Cooney; Christopher J Lynch
Journal:  Am J Physiol Endocrinol Metab       Date:  2007-10-09       Impact factor: 4.310

7.  Kinase activator protein mediates longer-term effects of starvation on activity of pyruvate dehydrogenase kinase in rat liver mitochondria.

Authors:  G S Denyer; A L Kerbey; P J Randle
Journal:  Biochem J       Date:  1986-10-15       Impact factor: 3.857

8.  Acute regulation of the branched-chain 2-oxo acid dehydrogenase complex by adrenaline and glucagon in the perfused rat heart.

Authors:  E F Hildebrandt; D B Buxton; M S Olson
Journal:  Biochem J       Date:  1988-03-15       Impact factor: 3.857

9.  Longer-term regulation of branched-chain-2-oxoacid dehydrogenase complex studied in rat hepatocytes in culture.

Authors:  M Beggs; J M Shaw; P J Randle
Journal:  Biochem J       Date:  1989-01-01       Impact factor: 3.857

10.  Modulation of rat skeletal muscle branched-chain alpha-keto acid dehydrogenase in vivo. Effects of dietary protein and meal consumption.

Authors:  K P Block; R P Aftring; W B Mehard; M G Buse
Journal:  J Clin Invest       Date:  1987-05       Impact factor: 14.808

  10 in total

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