Literature DB >> 3798047

Bradycardia after high-dose intravenous methylprednisolone therapy.

N Tvede, L P Nielsen, V Andersen.   

Abstract

In 5 consecutive patients with rheumatoid arthritis who received intravenous high-dose methylprednisolone (MP) therapy (1 g daily for 2 or 3 consecutive days), a decline in pulse rate was observed, most pronounced on day 4. In one of the 5 patients the bradycardia was associated with complaints of substernal pressure. Reversal to normal heart rate was found on day 7. Electrocardiographic registrations showed sinus bradycardia in all cases. No significant changes in plasma concentrations of electrolytes were found. Careful observation of patients receiving high-dose MP is recommended. High-dose MP may be contraindicated in patients with known heart disease.

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Year:  1986        PMID： 3798047     DOI： 10.3109/03009748609092597

Source DB:  PubMed          Journal:  Scand J Rheumatol        ISSN： 0300-9742            Impact factor:   3.641


  17 in total

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Authors:  S Sauerland; M Nagelschmidt; P Mallmann; E A Neugebauer
Journal:  Drug Saf       Date:  2000-11       Impact factor: 5.606

2.  Sudden death after treatment with pulsed methylprednisolone.

Authors:  P V Gardiner; I D Griffiths
Journal:  BMJ       Date:  1990-01-13

3.  Corticosteroid-induced bradycardia: Case report and review of the literature.

Authors:  Jasmine Stroeder; Charity Evans; Holly Mansell
Journal:  Can Pharm J (Ott)       Date:  2015-09

4.  High dose intravenous methylprednisolone pulse therapy in patients with rheumatoid arthritis.

Authors:  N Kapisinszky; B Keszthelyi
Journal:  Ann Rheum Dis       Date:  1990-07       Impact factor: 19.103

Review 5.  Corticosteroid-induced adverse events in adults: frequency, screening and prevention.

Authors:  Laurence Fardet; Abdulrhaman Kassar; Jean Cabane; Antoine Flahault
Journal:  Drug Saf       Date:  2007       Impact factor: 5.606

6.  First report of supraventricular tachycardia after intravenous pulse methylprednisolone therapy, with a brief review of the literature.

Authors:  Rakesh Kumari; S S Uppal
Journal:  Rheumatol Int       Date:  2005-02-23       Impact factor: 2.631

7.  Reappraisal of Rasmussen's syndrome with special emphasis on treatment with high doses of steroids.

Authors:  D Chinchilla; O Dulac; O Robain; P Plouin; G Ponsot; J F Pinel; D Graber
Journal:  J Neurol Neurosurg Psychiatry       Date:  1994-11       Impact factor: 10.154

Review 8.  Dose-dependent bradycardia as a rare side effect of corticosteroids: a case report and review of the literature.

Authors:  Döndü Üsküdar Cansu; Erdal Bodakçi; Cengiz Korkmaz
Journal:  Rheumatol Int       Date:  2018-10-01       Impact factor: 2.631

9.  Efficacy of methylprednisolone pulse therapy in children with rheumatoid arthritis.

Authors:  Yahya Aghighi; Lida Attarod; Maryam Javanmard
Journal:  Clin Rheumatol       Date:  2008-07-05       Impact factor: 2.980

Review 10.  Biologic drugs and arrhythmic risk in chronic inflammatory arthritis: the good and the bad.

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Journal:  Immunol Res       Date:  2017-02       Impact factor: 2.829
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