Literature DB >> 3792543

Loss of quin 2 accompanies degranulation of mast cells.

P C Bibb, D E Cochrane, N Morel-Laurens.   

Abstract

Stimulation of quin 2 loaded mast cells in the presence of 1 mM extracellular calcium produced a rapid and sustained increase in quin 2 fluorescence. This was accompanied by degranulation and the release of histamine. When Ca was replaced by EGTA or when Mn was present, a decrease in fluorescence accompanied degranulation. The increase in quin 2 fluorescence accompanying stimulation of mast cells appears to be due to the interaction of extracellular Ca with quin 2 associated with the secretory granule matrix released upon exocytosis.

Entities:  

Mesh：

Substances：

Year:  1986        PMID： 3792543     DOI： 10.1016/0014-5793(86)81105-x

Source DB:  PubMed          Journal:  FEBS Lett        ISSN： 0014-5793            Impact factor:   4.124


  8 in total

1.  Generation of histamine-releasing activity from serum albumin by medium derived from stimulated neutrophils of rat.

Authors:  D E Cochrane; W Boucher; R E Carraway
Journal:  Br J Pharmacol       Date:  1989-06       Impact factor: 8.739

2.  Histidine decarboxylase from rat mast cells. Enhanced recovery in cell-free extracts and isotopic labelling.

Authors:  R S Feldberg; D A Iannitti; D E Cochrane
Journal:  Biochem J       Date:  1988-01-01       Impact factor: 3.857

3.  HMC-1 human mast cells synthesize neurotensin (NT) precursor, secrete bioactive NT-like peptide(s) and express NT receptor NTS1.

Authors:  David E Cochrane; Robert E Carraway; Kimberly Harrington; Melissa Laudano; Stephen Rawlings; Ross S Feldberg
Journal:  Inflamm Res       Date:  2011-09-17       Impact factor: 4.575

4.  Inhibitory effects of the neurotensin8-13 analogs Asp13-NT8-13 and Asp12-NT8-13 on mast cell secretion.

Authors:  L A Miller; D E Cochrane; R E Carraway; R S Feldberg
Journal:  Agents Actions       Date:  1993-01

5.  Biphasic increase in cytosolic free calcium induced by bradykinin and histamine in cultured tracheal smooth muscle cells: is the sustained phase artifactual?

Authors:  Y Amrani; A Da Silva; O Kassel; C Bronner
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1994-12       Impact factor: 3.000

6.  Formation of histamine-releasing activity from albumin by medium conditioned by endotoxin-stimulated rat peritoneal macrophages.

Authors:  D E Cochrane; W Boucher; R E Carraway
Journal:  Agents Actions       Date:  1992-01

7.  The influence of intracellular calcium concentration on degranulation of dialysed mast cells from rat peritoneum.

Authors:  E Neher
Journal:  J Physiol       Date:  1988-01       Impact factor: 5.182

8.  Synergistic signals in the mechanism of antigen-induced exocytosis in 2H3 cells: evidence for an unidentified signal required for histamine release.

Authors:  M A Beaven; D F Guthrie; J P Moore; G A Smith; T R Hesketh; J C Metcalfe
Journal:  J Cell Biol       Date:  1987-09       Impact factor: 10.539
  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.